Enligt statistiken år 2010 fanns det 26 individer sett från en grupp på 100.000 som var tilldelade oxygenbehandling i hemmet. Oxygenbehandlingen tillför en bestämd mängd oxygen till bäraren då möjligheten att själv förse sig med rätt mängd för överlevnad hämmats. Den dominerande sjukdomen till oxygenbehandling i hemmet är KOL, kroniskt obstruktiv lungsjukdom. Som namnet antyder är det en kronisk sjukdom som ger inflammatoriska förändringar i lungans bronkioler. Dessa förändringar minskar andningsytan vilket resulterar i att individens andningskapacitet reduceras. Projektet använde metoder från dynamisk produktutveckling med användaren i fokus. Detta för att få fram en funktionell prototyp som kunde användas utav avsedd målgrupp och uppfylla det syfte, mål och krav som ställdes på projektets resultat. En viktig komponent som projektet därför arbetade med var insamling av data. För detta användes olika metoder som kunde tillskaffa sig information från både användare och förskrivare av oxygenbehandling.  Samtliga av de metoder som användes var beprövade sedan tidigare och projektet kunde därför med fördel genomföra intervjuer, observationer, matrisuppställningar, riskanalyser samt användartester på patienter med oxygenbehandling. Prototypen som togs fram i projektet resulterade i att avsedd målgrupp kunde utföra testmoment på den utan att det förekom risker med användandet. Resultatet uppfyllde därför syftet och målet med projektet som riktade sig mot att patienter skulle få möjlighet till att förflytta den syrgasslang som används vid oxygenbehandling. Vidare kunde slutsatsen dras att resultatet uppfyllde patienternas önskemål om att ta fram en möjlighet till förflyttning av syrgasslangen i hemmet samtidigt som det besvarade de frågeställningar som projektet strävade efter att besvara. Det fanns inga befintliga lösningar på det problem som beskrevs i projektet och det gav möjlighet att framställa en första prototyp som uppfyllde syftet och målet. / According to statistics, in 2010 there were 26 individuals seen by a group of 100,000 who were depending in home oxygen therapy (HOT). Oxygen treatment adds a certain amount of Oxygen to the patient because the ability to breathe correctly and sufficiently is negatively affected. The dominant disease that leads to HOT is COPD, chronic obstructive pulmonary disease. As the name suggests, it is a chronic disease which gives inflammatory changes to the lung bronchioles. These changes affect the breathing surface which results in that the individuals’ respiratory capacity becomes reduced. The project used methods from dynamic product development with the user in focus. This to obtain a functional prototype that could be used by the target group and to fulfill the purpose, goals and requirements set for the project's results. An important component of the project therefore was to work with the collection of data. For this, various methods were used to obtain information from users as well as prescribers of HOT. All of the methods used have been tested earlier and proven reliable. This project collected information from interviews, observations, matrix arrays, risk analysis and usability testing in patients with HOT. The prototype developed in the project resulted in that the target group could perform live test without any risks during testing. The results showed that the aim and objective for the project were fulfilled, expressed in that patients would be able to move the oxygen tube used in HOT. It was further concluded that the results fulfilled the patients' desire and opportunity to move the Oxygen tube in their home and at the same time answered the questions that the project was to answer. There were no existing solutions to the problem which is included in the project, but it was possible to develop a first prototype that met the purpose and object of the project.

[Truncated abstract] Therapeutic Radiation has been used for the treatment of cancer and other diseases for nearly a century. Over the past 20 years, Hyperbaric Oxygen Treatment (HBOT) has been used to assist wound healing in the prevention and treatment of the more severe complications associated with the side effects of Therapeutic Radiation Treatment (TRT). The use of HBOT is based on the premise that increased oxygen tissue tension aids wound healing by increasing the hypoxic gradient and stimulating angiogenesis and fibroblast differentiation. As it takes up to 6 months for a hypoxic state to develop in treated tissue, following radiation treatment, current recommendations for HBOT state that it is not effective until after this time. During this 6 month period, immediately following TRT, many specialized tissues in or adjacent to the field of irradiation, such as salivary glands and bone, are damaged due to a progressive thickening of arteries and fibrosis, and these tissues are never replaced. Currently, HBOT is used to treat the complications of TRT, but it would be far better if they could be prevented . . . In summary, this experimental model has fulfilled its prime objective of demonstrating that HBOT is effective in reducing the long-term side effects of therapeutic radiation treatment in normal tissue, when given one week after the completion of the radiation treatment and statistically disproves the Null Hypothesis that there is no difference in the incidence of postoperative complications or morbidity of TRT when 20 intermittent daily HBOT are started one week after completion of TRT. This project provides an extensive description of the histological process and also proposes a hypothesis for the molecular events that may be taking place.