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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
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Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 1 to 10 of 45 (0.023 seconds)Spelling suggestions: "subject:"oxygenases"" "subject:"dioxygenases""
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Purification of 2,5-dihydroxyacetanilide epoxidase and mechanism of hydroquinone epoxidasesKirchmeier, Marc J. 12 June 1997 (has links)
2,5-dihydroxyacetanilide epoxidase from Streptomyces LL-C10037 (DHAE I)
catalyzes the epoxidation of hydroquinone 4, to form epoxyquinone 7. DHAE I has been
purified to homogeneity, with an overall purification factor greater than 23,000. N-terminal
and internal amino acid sequences have been obtained from the purified enzyme so
that the epoxidase gene may be cloned by using reverse genetics.
The epoxidation reaction of DHAE I requires only molecular oxygen and no added
cofactors. The detailed chemical mechanism has been elucidated using isotopically labeled
oxygen. DHAE I is a dioxygenase belonging to a new and unrecognized class of
dioxygenases that are described as "hydroquinone epoxidizing dioxygenases."
DHAE I and another epoxidizing enzyme which acts on the same substrate but
producing the enantiomeric epoxide, DHAE II from Streptomyces MPP 3051, have had
their active sites examined for structural latitude. DHAE II shows more flexibility toward
substrate analogs than DHAE I. However, both enzymes are very specific for the correct
substrate. From these studies, crude three dimensional models of the two active sites have
been constructed. / Graduation date: 1998
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| 2 |
Mechanistic studies on protocatechuate 3, 4-dioxygenaseOldham, Charlie Daniel 12 1900 (has links)
No description available.
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| 3 |
Purification, physicochemical properties, and kinetic mechanism of a steroid dioxygenaseTai, Hsin-Hsiung, January 1970 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1970. / Typescript. Vita. Description based on print version record. Includes bibliographical references.
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| 4 |
Structure and function of the human FMOs : tissue localization, comparative modeling, and kinetic parameters of FMO3 allelic variants /Yeung, Catherine K. January 2005 (has links)
Thesis (Ph. D.)--University of Washington, 2005. / Vita. Includes bibliographical references (leaves 182-200).
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| 5 |
Mechanistic studies on the epoxidation of P OleovoransKatopodis, Andreas George 08 1900 (has links)
No description available.
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| 6 |
The isolation of protocatechuate-3, 4-dioxygenase and investigations into the nature of the ligands of the active site ironSowell, Anne Lorraine 08 1900 (has links)
No description available.
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| 7 |
Synthesis, enzymology, and pharmacology of novel oxygenase substrates and inhibitors: dopamine [beta]-monooxygenase and protocatechuate 3,4-dioxygenasePadgette, Stephen R. 12 1900 (has links)
No description available.
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| 8 |
Correlation of antihypertensive activity of novel DBM substrates with adrenergic catecholamine levels in spontaneously hypertensiveEvans, Chheng-Orn Ny 05 1900 (has links)
No description available.
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| 9 |
Mechanistic and biotechnological investigations of pseudomonas oleovorans monooxygenase and enantiospecificity of dopamine B-monooxygenaseColbert, James Early, Jr. 05 1900 (has links)
No description available.
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| 10 |
Isotopic probe for spectroscopic studies of hemeManjunath, Sandhya C. January 1900 (has links)
Thesis (M.S.)--The University of North Carolina at Greensboro, 2009. / Directed by Gregory Raner; submitted to the Dept. of Chemistry and Biochemistry. Title from PDF t.p. (viewed Jun. 7, 2010). Includes bibliographical references (p. 58-59).
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