Global ETD Search

1	C-fos induction in spinal neurons by sensory stimulation Williams, Timothy Simon Carl January 1991 (has links) No description available. 571.4 Pain mechanisms
2	Properties of trigeminal brainstem neurones and their modulation by peripheral conditioning stimuli in cats Kuriakose, Maria January 1994 (has links) No description available. 571.4 Pain mechanisms
3	The influence of stimulus control on the effects of transcutaneous electrical nerve stimulation (TENS) on experimental ischaemic pain Kirk, Kerry Alicia January 1997 (has links) A review of the relevant literature suggested a number of unresolved issues in the most efficacious use of TENS for pain-relief including the degree of control and the frequency of TENS. The study investigated the influence of giving subjects control of the TENS stimulus on reported pain intensity and unpleasantness during experimental ischaemic pain induction of the arm. The pain induction and assessment procedures were established during an initial series of three experiments. Subjects in these and the subsequent experiments were healthy female student volunteers from Queen Margaret College. A further series of experiments investigated the influence of control of the TENS intensity on VAS scores of pain intensity and unpleasantness. When used, TENS (symmetrical biphasic current; pulse duration 200ýts; intensity 'just perceptible') was applied for the 15 minutes prior to cuff inflation and during the 15 minutes of pain induction (electrodes placed over Erb's point and lateral to C6/7). The first TENS experiment investigated the. influence of three different conditions (experimenter controlling TENS intensity; subject controlling TENS intensity; no TENS) using high frequency (100Hz) TENS. All subjects (n=12) were randomly exposed to the three testing conditions using a repeated measures design. A 2-way ANOVA with repeated measures on both factors showed no statistically significant effects (p≥0.05) on either VAS pain intensity or unpleasantness scores. The procedure was repeated with different subjects (n=12) using low frequency (5Hz) TENS. The results showed that mean pain scores were statistically significantly lower (p≤0.05) in the subject control condition than in the other two conditions (experimenter control and no TENS). A final experiment (n=12) compared VAS pain intensity and unpleasantness scores between the three conditions of, subject controlling 100Hz TENS, subject controlling 5Hz TENS and no TENS. The results demonstrated a trend for the 5Hz TENS condition to give lower mean pain scores than the other two conditions with both intensity (p=0.239) and unpleasantness scores (p=0.110). From the results and discussion it was suggested that the pain-relieving benefit of TENS was enhanced when the subjects were given control of the current intensity, especially when using low frequency TENS. The clinical implications of the results are discussed. 615.5 Pain mechanisms
4	The role of different 5-HT receptor subtypes in modulating nociception in the rat El-Yassir, Nada January 1989 (has links) No description available. 571.4 Pain mechanisms/responses
5	Temporal Dynamics of Heat Pain Sensations Hashmi, Javeria Ali 13 August 2010 (has links) The moment-to-moment fluctuations in pain-evoked sensory and emotional qualities, and how the pain experience differs between sexes are not well understood. Therefore, this thesis sought to 1) characterise the temporal profiles of the most prominent noxious heat-evoked sensations, 2) characterise sex differences in these sensations, 3) evaluate the magnitude of sharp pain quality evoked in hairy and glabrous skin, and 4) determine the role of absolute stimulus temperatures on sex differences in pain adaptation and habituation. A broad-based heat pain model was developed for this study that incorporates a temporally-continuous assessment of multiple sensory and affective pain dimensions, including pain, burning, sharp, stinging, cutting, and annoyance evoked by two types (static, dynamic) of repeated prolonged noxious heat stimuli. The salient hypotheses were: 1) Burning sensations have a different temporal profile compared with sharp and other related qualities, 2) The temporal dynamics of heat pain intensity and annoyance differ between males and females, 3) Sex differences in heat pain are associated with specific pain qualities and specific types of skin, and 4) Moderate-high temperatures induce pain adaptation and habituation in females but not in males. The most prominent findings were 1) sharp, stinging and cutting sensations adapted when stimulus intensity was static, but burning sensations were evoked during static and dynamic stimulus phases, 2) pain and annoyance in women were greater than men during the dynamic phases of the first stimulus but less than men during static stimulus phases and on stimulus repetition, 3) the sex difference in pain adaptation occurred with percept-fixed stimulus intensities and with absolute stimulus temperatures, 4) the sex effects associated with dynamic stimuli occurred in hairy but not glabrous skin. These findings give new insights into the relationships between pain intensity, quality and affect and have strong implications for views on sex differences in pain sensitivity. Pain, sex differences in pain pain patterns temporal summation psychophysics tonic pain burning adaptation models habituation temporal heat pain temperature pain modulation glabrous hairy analgesia chronic pain sex women sex differences sharp pain mechanisms a-delta unmyelinated C fibre brain MPQ pain dimensions 0317 0384 0349 0989 0632
6	Temporal Dynamics of Heat Pain Sensations Hashmi, Javeria Ali 13 August 2010 (has links) The moment-to-moment fluctuations in pain-evoked sensory and emotional qualities, and how the pain experience differs between sexes are not well understood. Therefore, this thesis sought to 1) characterise the temporal profiles of the most prominent noxious heat-evoked sensations, 2) characterise sex differences in these sensations, 3) evaluate the magnitude of sharp pain quality evoked in hairy and glabrous skin, and 4) determine the role of absolute stimulus temperatures on sex differences in pain adaptation and habituation. A broad-based heat pain model was developed for this study that incorporates a temporally-continuous assessment of multiple sensory and affective pain dimensions, including pain, burning, sharp, stinging, cutting, and annoyance evoked by two types (static, dynamic) of repeated prolonged noxious heat stimuli. The salient hypotheses were: 1) Burning sensations have a different temporal profile compared with sharp and other related qualities, 2) The temporal dynamics of heat pain intensity and annoyance differ between males and females, 3) Sex differences in heat pain are associated with specific pain qualities and specific types of skin, and 4) Moderate-high temperatures induce pain adaptation and habituation in females but not in males. The most prominent findings were 1) sharp, stinging and cutting sensations adapted when stimulus intensity was static, but burning sensations were evoked during static and dynamic stimulus phases, 2) pain and annoyance in women were greater than men during the dynamic phases of the first stimulus but less than men during static stimulus phases and on stimulus repetition, 3) the sex difference in pain adaptation occurred with percept-fixed stimulus intensities and with absolute stimulus temperatures, 4) the sex effects associated with dynamic stimuli occurred in hairy but not glabrous skin. These findings give new insights into the relationships between pain intensity, quality and affect and have strong implications for views on sex differences in pain sensitivity. Pain, sex differences in pain pain patterns temporal summation psychophysics tonic pain burning adaptation models habituation temporal heat pain temperature pain modulation glabrous hairy analgesia chronic pain sex women sex differences sharp pain mechanisms a-delta unmyelinated C fibre brain MPQ pain dimensions 0317 0384 0349 0989 0632

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