Objectives To understand the acceptability of adult males, high-risk male population (MSM and bisexual men) and parents of adolescent sons and explore factors correlated with HPV vaccination acceptability Methods A systematic searching process for literatures related to men’s HPV vaccination acceptability and published from 2000 to July, 2013 in PubMed, MEDLINE, CINAHL, Cochrane Library and Google Scholar was performed. After screening based on inclusion and exclusion criteria, qualities of all eligible studies were assessed based on the modified STROBE guideline. Results Of 15 studies were included in this systematic review, 6 focused on adult males, 4 explored the high-risk males, five reported the parental acceptability. The HPV vaccination acceptability of adult males, high-risk male population and parents of adolescent sons was moderate or high in most reviewed studies. Knowledge about HPV and HPV vaccination, perceived susceptibility, perceived benefits and healthcare provider’s recommendation were positively correlated with HPV vaccination acceptability among adult males, high-risk males and parents of adolescent sons while high expense, side effects, safety, uncertain effectiveness and hassle of receiving a 3-shots series of HPV vaccination could diminish people’s vaccination interest. Conclusion HPV vaccination acceptability among adult males, high-risk males and parents of adolescent sons is moderate or high. Further HPV vaccine campaign should focus on bridging the gap between the high vaccination acceptability and the low vaccination uptake among males. / published_or_final_version / Public Health / Master / Master of Public Health

In an age of biomedicine, technologies, drugs, and treatments are expanding in new and diverse ways. Especially relevant to biomedicalization and this research is how such information is conveyed to the public through the media. Medical information is omnipresent in the media through direct-to-consumer (DTC) advertising and regular coverage of health topics in the news. The accessibility and proliferation of medical information provides an important opportunity to examine the ways in which these topics are framed in the media. This research specifically examines the framing of the HPV vaccine, Gardasil in the mass media. In this study, I explore how Gardasil was framed, how gender and sexuality were utilized within such frames, and what groups influenced these frames. I employ frame analysis to examine the presentation of Gardasil in the mass media. Due to the vaccine's intricate connection to gender and sexuality, I examine how these dimensions are utilized and reproduced in such frames. Gardasil was originally approved only for women, making gender a salient aspect of the vaccine. The current body of research examining Gardasil in the media presents data from the time the vaccine was only available to women. Now that the HPV vaccine is approved for men, this research seeks to contribute to a more comprehensive understanding of how Gardasil was framed in the media now that it is available to men and women. And given that Gardasil prevents a sexually transmitted infection (STI) in men and women, it is uniquely tied to issues of sexuality. To analyze Gardasil in the media, I examine newspaper articles, magazine articles, and media representations from stakeholder groups, including DTC advertising, official statements, and group websites. Analysis of key sources indicates that Merck dominated the framing of the vaccine in DTC advertisements and the news media, illustrating the power of the pharmaceutical industry. Findings indicate that the initial marketing of Gardasil constructed the vaccine as uniquely tied to femininity and later, women's empowerment. However, once the drug was approved for men, messages were reframed to appeal to a wider audience. Overall, the media continued to frame the vaccine specifically for women, further constructing HPV as a "woman's disease." The dominant focus on women concomitantly silenced the sexual health of men and sexual minorities. In conclusion, the marketing, discourse, and structural elements of Gardasil make it less accessible to those most in need, therefore contributing to the ongoing problem of cervical cancer and HPV.