Many variables have been analyzed in order to understand parent-adolescent interactions and outcomes for adolescents. These variables must be integrated into a model that demonstrates the holistic interplay of parent-adolescent interaction variables so that a more comprehensive understanding of parent-adolescent interactions is achieved. Variables included in the model proposed here were parenting, family environment, expectations, conflict, and outcomes. Parenting, family environment, and conflict were associated with outcomes for adolescents. When the variables were analyzed simultaneously with structural equation modeling, however, the relationship of parenting and adolescent outcomes was mediated wholly for male-father, male-mother, and female-father relationships but remained significant for female-mother relationships. Overall, the holistic interplay of parent-adolescent interaction variables and the need to examine parent-adolescent dyads individually were demonstrated.