The present study examined the relations among maternal psychological control, maternal acceptance, maternal acculturation and youth anxiety within the framework of a (partially) moderated mediation model. The sample consisted of 535 Hispanic-Latino youth (46% girls; M = 9.79 years) and their mothers. The study’s data were analyzed using structural equation modeling in the MPlus statistical software program. Results indicated that maternal psychological control and youth anxiety are significantly and positively related. Results also indicated that more acculturated mothers were more psychologically controlling than less acculturated mothers. Results further provided evidence for a partial mediational role of maternal psychological control on the relation between maternal acculturation and youth anxiety symptoms. In addition, there was a direct, positive relation between maternal acculturation and youth anxiety symptoms. No significant findings were observed regarding the moderating role of maternal acceptance on the relation between maternal psychological control and youth anxiety. The findings’ theoretical and clinical implications are further discussed.