This thesis comprises two studies that investigated bike infrastructure safety in North America. The first study conducted a corridor-level analysis to quantify the safety of different bike infrastructure types and assess the influence of corridor-specific characteristics on their performance. Using a Poisson-lognormal Full Bayesian model, the study analyzed fatal and injury bike-vehicle collisions on over 7800 corridors in Toronto, Canada. The findings revealed that bike infrastructure effectively reduces bike collisions, with cycle tracks demonstrating superior safety benefits due to the physical separation of cyclists from vehicular traffic. Cycle tracks were found to be particularly effective on long corridors with fewer intersections as bike-vehicle interactions along the corridor are minimized. Signed routes were safe on low-volume and low-speed roads, while bike lanes are more suited for a short section of high-volume corridors with a high intersection density. The second study assessed the safety of parking-protected bike lanes (PPBL), a new concept that is rapidly growing in North America. Utilizing data from nineteen street sections in Vancouver and Ottawa, the study developed a Full Bayesian Before-and-after model to evaluate the safety impacts of converting traditional painted bike lanes to PPBLs. The results indicated a significant reduction of 31.2% in total collisions after PPBL implementation. However, the effects of PPBLs on cyclist safety were found to be sensitive to factors such as bike path opening density, intersection density, and intersection treatments. In roads where proper intersection treatments and minimal protection of PPBL openings can be provided, painted bike lanes can be converted into PPBLs, and significant safety benefits can be expected. The findings of this thesis offer practical guidance for city planners and policymakers regarding the safety implications of different bike infrastructure types and the most appropriate conditions to implement them, which supports bike safety enhancement initiatives and attracts more people to bike. / Thesis / Master of Applied Science (MASc) / This thesis presents two studies that offer valuable insights to improve bike safety. The first study examined the safety of various bike infrastructure types along with the impact of corridor characteristics on their performance. The findings emphasized the effectiveness of cycle tracks in reducing collisions on long corridors with fewer intersections. Signed routes were found to be effective on low-volume and low-speed roads, while bike lanes were ideal on short sections of high-volume roads with a high intersection density. The second study assessed the impacts of new designed concept, known as the parking-protected bike lanes (PPBLs). The study showed that converting painted bike lanes to PPBLs significantly reduced total collisions. However, proper treatment of intersection and bikeway openings is crucial for enhancing cyclist safety and reducing multi-vehicle rear-end collisions. Where proper intersection treatment and minimal protection of bikeway openings can be provided, bike lanes can be safely converted into PPBLs.