Knowledge transfer is an interaction between knowledge receiver and provider. They acquire new knowledge through all kinds of media during this process. Furthermore, they assimilate, develop, innovate, and apply it. When there is some knowledge lacked inside an organization, there will be a knowledge gap. In order to bridge the knowledge gap, they need to obtain external knowledge through knowledge transfer. Knowledge transfer is the most important and difficult one in all of the knowledge management issues. The study is to analyze the important factors, which influence knowledge transfer by probing into the process of information system development. This study develops based on the research of Harald et al. (2002). Three contexts of constructs influencing knowledge transfer were induced: (1) domain knowledge dimension, including tacitness, complexity, and specificity, (2) system development team dimension, including system development experience and the degree of domain knowledge understanding, (3) partnership quality, including trust, mutual understanding, benefit and risk sharing, and commit. This study focuses on these three constructs to find the impacts on knowledge transfer performance. This study tested the impact of knowledge transfer on ISD performance, and analyzed the critical factors influencing inter-team knowledge transfer through empirical survey. And the samples are the members of domestic system development teams. The research result reveals that knowledge transfer performance has significant impact on system development performance. On the other hand, partnership quality has the most impact on knowledge transfer performance and system development experience is the next. Furthermore, ISD performance is affected by partnership quality, too. This result will provide a different point of view of ISD, which can guide teams to produce more successful systems from the knowledge management perspective.