Educational Intervention to Impact Parental Decisions to Consent to Human Papillomavirus Vaccine by Tawa B. Ibikunle-Salami MSN, Indiana Wesleyan University, 2010 BSN, Indiana Wesleyan University, 2005 Project Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University September 2015 Human Papillomavirus (HPV) is a global health issue that is transmitted sexually and affects both genders. Evidence shows that approximately 79 million people are affected in the United States with 14 million newly affected yearly. The Centers for Disease Control and Prevention indicates that teens and young adults under age 25 are at particular risk, so it is important to begin the vaccination series between 9 and 17 years of age. Parental voluntary acceptance of HPV vaccine for their minor children was noted as a problem in a clinic in Northwest Indiana, and 8% clinic HPV series completion rate is significantly lower than the targeted federal goal of 80% by 2020. A literature review indicated that an educational intervention provided by healthcare professionals could serve as one of the strongest predictors of HPV vaccine acceptance. The purpose of this project was to develop an evidence-based parental educational process to support providers' influence on parents of children ages 9 to 17 to provide consent for the HPV vaccine. The project goals focused on parental knowledge, beliefs, and attitudes. The clinic providers will utilize assessment tools validated by experts and evidence-based educational materials to promote HPV and HPV vaccine awareness. The theoretical foundations of the project were the theory of reasoned action and Pathman's pipeline that target the parents directly through individual educational sessions to achieve knowledge gain and behavioral change. Implementation of educational materials by clinic providers may improve parental knowledge of HPV and the HPV vaccine acceptance. Social change may result from the integration of the project into clinical practice to increase the HPV vaccine acceptance rates, which will ultimately reduce the effects of HPV and its sequelae leading to long-term wellness promotion.