Copies of author's previously published articles inserted. / Bibliography: leaves 267-303. / xviii, 304 leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Experiments described in the thesis address the anti-aggregatory effects and mechanism of action of the prophylactic anti-anginal agent perhexiline maleate. In particular, it was sought to examine if perhexiline had an anti-aggregatory effect which may contribute to its proven therapeutic efficacy. / Thesis (Ph.D.)--University of Adelaide, Dept. of Physiology, 2000

Appendum consists of last two leaves. / Copies of author's previously published articles inserted. / Bibliography: leaves 241-283. / xviii, 284 leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / The studies described were designed to identify and address (through the application of relatively novel and potentially useful adjunctive therapeutic strategies) some of the determinants of sub-optimal therapeutic response in intermediate coronary syndrome and chronic congestive heart failure; especially when targeted towards those patients who fail to gain the maximal benefit from pre-existing modalities of pharmacological treatment. / Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1999