Thesis (M.Sc.)--University of Alberta, 2009. / A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Master of Science in Experimental Surgery, Department of Surgery. Title from pdf file main screen (viewed on September 15, 2009). Includes bibliographical references.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1961. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

by Leung Shiu Man. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1990. / Bibliography: leaves 137-146. / Chapter CHAPTER ONE --- Introduction --- p.1 / Chapter 1.1 --- Surgical intervention done for nerve injury --- p.1 / Chapter 1.2 --- Rehabilitation procedures after nerve injuries --- p.2 / Chapter 1.3 --- Frustrating result of recovery after nerve injuries --- p.3 / Chapter 1.4 --- Reasons for the poor results --- p.3 / Chapter 1.5 --- Objective of the study --- p.5 / Chapter 1.6 --- Hypothesis and organization of the study --- p.6 / Chapter CHAPTER TWO --- The effects of pulsed electromagnetic field on peripheral nerve regeneration --- p.8 / Chapter 2.1 --- Electrical field and nerve growth --- p.8 / Chapter 2.2 --- Experimental findings of effect of the electromagnetic field on peripheral nerve regeneration --- p.9 / Chapter 2.3 --- The diversity of interest --- p.17 / Chapter CHAPTER THREE --- Physiological effects of the pulsed electromagnetic field --- p.18 / Chapter 3.1 --- The conventional use of electromagnetic field in musculoskeletal rehabilitation --- p.18 / Chapter 3.2 --- The pulsed electromagnetic field --- p.18 / Chapter 3.3 --- Nature of the pulsed electromagnetic field with a carrier frequency of 27.12 MHz --- p.19 / Chapter 3.4 --- Therapeutic effects of the pulsed electromagnetic field --- p.20 / Chapter 3.5 --- Some experimental results of the pulsed electromagnetic field --- p.20 / Chapter 3.6 --- Discussion --- p.25 / Chapter CHAPTER FOUR --- Methology --- p.27 / Chapter 4.1 --- Experimental animals and aneasthesia --- p.27 / Chapter 4.2 --- Models of lesions --- p.28 / Chapter 4.3 --- Sample size and grouping of the experimental rats --- p.35 / Chapter 4.4 --- Pulsed electromagnetic field stimulation --- p.37 / Chapter 4.5 --- Methods of evaluating the nerve regeneration --- p.38 / Chapter 4.6 --- Statistical analysis --- p.53 / Chapter CHAPTER FIVE --- Results --- p.54 / Chapter 5.1 --- Directly repaired groups --- p.54 / Chapter 5.2 --- Crushed groups --- p.62 / Chapter 5.3 --- Artery bridge groups --- p.73 / Chapter 5.4 --- Sham operated groups --- p.84 / Chapter 5.5 --- Electron microscopic examination --- p.90 / Chapter 5.6 --- Summary of all the data --- p.94 / Chapter CHAPTER SIX --- Discuss ion --- p.96 / Chapter CHAPTER SEVEN --- Conclusion --- p.103 / Chapter 7.1 --- Restatement of the experimental objective and hypothesis --- p.103 / Chapter 7.2 --- Conclusion --- p.103 / Chapter 7.3 --- Suggestions for furthur research --- p.104 / Chapter 7.4 --- Clinical Implication --- p.105 / Chapter APPENDIX I --- Determination of the duration of survival of the experimental animal --- p.106 / Chapter APPENDIX II --- Perfusion of rats --- p.115 / Chapter APPENDIX III --- Horseradish peroxidase and tetramethvlbezindine reaction --- p.118 / Chapter APPENDIX IV --- Histology fixation --- p.120 / Chapter APPENDIX V --- Determination of the Position of the Histology Specimens --- p.121 / Chapter APPENDIX VI --- Raw Data Collected in the Experiment --- p.132 / REFERENCE --- p.137

Ph.D.

Diss. (sammanfattning) Stockholm : Karol. inst., 2002. / Härtill 5 uppsatser.

Thesis (doctoral)--Lund University, 1997. / Added t.p. with thesis statement inserted.

Thesis (doctoral)--Lund University, 1997. / Added t.p. with thesis statement inserted.

Ph.D.

Diss. (sammanfattning) Stockholm : Karol inst., 2004. / Härtill 4 uppsatser.

yes / There is a clinical need for novel graft materials for the repair of peripheral nerve defects. A decellularisation process has been developed for porcine peripheral nerves, yielding a material with potentially significant advantages over other devices currently being used clinically (such as autografts and nerve guidance conduits). Grafts derived from xenogeneic tissues should undergo sterilisation prior to clinical use. It has been reported that sterilisation methods may adversely affect the properties of decellularised tissues, and therefore potentially negatively impact on the ability to promote tissue regeneration. In this study, decellularised nerves were produced and sterilised by treatment with 0.1% (v/v) PAA, gamma radiation (25-28 kGy) or E Beam (33-37 kGy). The effect of sterilisation on the decellularised nerves was determined by cytotoxicity testing, histological staining, hydroxyproline assays, uniaxial tensile testing, antibody labelling for collagen type IV, laminin and fibronectin in the basal lamina, and differential scanning calorimetry. This study concluded that decellularised nerves retained biocompatibility following sterilisation. However, sterilisation affected the mechanical properties (PAA, gamma radiation), endoneurial structure and basement membrane composition (PAA) of decellularised nerves. No such alterations were observed following E Beam treatment, suggesting that this method may be preferable for the sterilisation of decellularised porcine peripheral nerves.