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No. of bitstreams: 1 TES_M?RCIA DE C?SSIA CASSIMIRO.pdf: 2463749 bytes, checksum: 385f8cdc256f0fbd00f0f9b9f4ee466b (MD5) Previous issue date: 2018-08-29 / This thesis investigates based on Axel Honneth's Theory of Recognition, Conflicts of Interest [COIs] and integrity in the process of emancipation and management of a diversity of border issues such as: disrespect [Mi?achtung] and violation [Verletzung] to the citizen, capable of provoking profound transformations and changes to society in the face of the peculiar characteristics of a concrete social reality of participatory democratic domination. The thesis discusses the impact of violations on patients, research participants, society, and institutions; besides issues related to injustice and dishonesty arising from misconduct. COIs and misconduct provoke political, technical, ethical, and moral offenses when individuals are affected | violated in nonrecognition dynamics. The three patterns [affective, legal, solidarity] can have as consequence: [i] psychic death in the first pattern of [affective] recognition; [ii] social death in the second [legal] standard; and [iii] social humiliation in the third standard [solidarity]. The struggle for recognition is the condition for conflicts to be normative. There are models of justice such as: redistributive; economist, and recognition. But this thesis is delimited around the contribution of recognition to the theoretical confrontation of COIs and integrity. It is presumed that the struggle for recognition is a fundamental element in order to initiate research on COIs and integrity, thus articulating an interdisciplinary approach [Philosophy and Health]. COIs is a set of circumstances or conditions in which professional judgment of a primary interest such as integrity and quality in research tends to be unduly influenced by a secondary interest such as personal financial gain. COIs are classified into primary and secondary interests. Primary interests are determined by the professional duties of the researcher, physician, counselor and other professionals of the institution, and are related to the integrity of these different actors, and to the patient's well-being. Secondary interests are any type of interest that may affect the primary interest priority. They are harmful when they influence, corrupt or distort integrity and affect the judgment of the practitioner in relation to patient health and integrity. In addition to the definition proposed by Emanuel et al. [2008], this research comprehensively covers several areas of knowledge and institutions [universities, pharmaceutical industries, editors, professional and patient associations, and Research Ethics Committees]. Integrity has broad domain with many emphases, and demands commitment from various actors [institution, citizen, governors, patients, development agencies, etc.], that is, it involves a more reflective point of view on guidelines focusing on the development of multiple spheres, abilities or even virtues of the individual. It is imperative to recognize that COIs in clinical research and violations of integrity affect not only health professionals but every society, thus justifying the citizen's struggle not only against social order but against the social place to which, at present, science is being condemned. This is not the sole responsibility of scientists, but of the whole society and in particular of its rulers, researchers and professionals. Partnerships between researchers, teaching and research institutions, universities, patient associations, government, laboratories and universities are important for the development of science. Therefore, there is no pretense of stigmatizing these partnerships involving different actors. / Esta tese investiga com base na Teoria do Reconhecimento de Axel Honneth, os Conflitos de interesses [COIs] e a integridade no processo de emancipa??o e manejo de uma diversidade de quest?es lim?trofes tais como: desrespeito [Mi?achtung] e viola??o [Verletzung] ao cidad?o, capazes de provocar profundas transforma??es e mudan?as ? sociedade em face das caracter?sticas peculiares de uma realidade social concreta de dom?nio democr?tico participativo. A tese discute o impacto das viola??es causadas aos pacientes, aos participantes de pesquisa, a sociedade, e as institui??es; al?m de quest?es relacionadas a injusti?a e desonestidade decorrentes da m? conduta. COIs e m? conduta provocam impasses pol?ticos, t?cnicos, ?ticos, e ofensa moral, quando os indiv?duos s?o afetados | violados em din?micas de n?o reconhecimento [nonrecognition]. Os tr?s padr?es [afetivo, jur?dico, solidariedade] podem ter como consequ?ncia: [i] morte ps?quica no primeiro padr?o de reconhecimento [afetivo]; [ii] morte social no segundo padr?o [jur?dico]; e [iii] humilha??o social no terceiro padr?o [solidariedade]. A luta por reconhecimento ? a condi??o para que os conflitos sejam normativos. H? modelos de justi?a tais como: redistributivo; economicista, e de reconhecimento. Mas esta tese ? delimitada em torno da contribui??o do reconhecimento para o enfrentamento te?rico dos COIs e da integridade. Presume-se que a luta por reconhecimento constitui elemento fundamental para instanciar a investiga??o sobre COIs e integridade, articulando desta forma uma abordagem interdisciplinar [Filosofia e Sa?de]. COIs ? um conjunto de circunst?ncias ou condi??es nas quais o julgamento profissional de um interesse prim?rio como integridade e qualidade na pesquisa tende ser influenciado indevidamente por um interesse secund?rio, como ganho financeiro pessoal. Os COIs s?o classificados em interesses prim?rios e secund?rios. Os interesses prim?rios s?o determinados pelos deveres profissionais do pesquisador, m?dico, orientador e demais profissionais da institui??o, e est?o relacionados ? integridade destes distintos atores, e ao bem-estar do paciente. Os interesses secund?rios s?o qualquer tipo de interesse que possa afetar a prioridade do interesse prim?rio. S?o prejudiciais quando influenciam, corrompem ou distorcem a integridade e afetam o julgamento do profissional em rela??o ? sa?de do paciente, e a integridade. Para al?m da defini??o proposta por Emanuel et al. [2008], de maneira ampla esta pesquisa abrange diversas ?reas do conhecimento e institui??es [universidades, ind?strias farmac?uticas, editores, associa??es profissionais e de pacientes, e Comit?s de ?tica em Pesquisa]. Integridade possui dom?nio amplo com v?rias ?nfases, e demanda compromisso de diversos atores [institui??o, cidad?o, governantes, pacientes, ag?ncias de fomento, etc.], ou seja, envolve um ponto de vista mais reflexivo sobre diretrizes com foco no desenvolvimento de m?ltiplas esferas, capacidades ou mesmo virtudes do indiv?duo. ? imprescind?vel reconhecer que os COIs em pesquisa cl?nica e as viola??es de integridade n?o afetam apenas os profissionais da sa?de, mas toda sociedade, justificando assim a luta do cidad?o n?o apenas contra a ordem social, mas contra o lugar social ao qual, na atualidade, a ci?ncia est? sendo condenada. Esta n?o ? uma responsabilidade exclusiva dos cientistas, mas de toda a sociedade e em particular dos seus governantes, pesquisadores e profissionais. Parcerias entre pesquisadores, institui??es de ensino e pesquisa, universidades, associa??es de pacientes, governo, laborat?rios e universidades s?o importantes para o desenvolvimento da ci?ncia. Portanto, n?o h? pretens?o de estigmatizar estas parcerias envolvendo distintos atores.