This dissertation investigates the effects of multisensory biophilic restorative experiences on how engineers feel, think, and design. While previous research on the restorative effects of biophilic experiences have mostly focused on the benefits of visual exposure, less is known about the potential of exposure to auditory and multisensory stimuli. Moreover, a knowledge gap exists in regards to how the cognitive benefits of biophilic restorative experiences influence performance in real-world cognitive tasks, like design. To address the identified knowledge gaps, a randomized controlled trial with 154 participants was conducted, exploring the restorative effects of biophilic auditory, visual, and multisensory (auditory + visual) experiences after induced psychosocial stress. To assess the potential influence on the performance of a real-world cognitive tasks, an open-ended design task was given to participants following the exposure period. Dependent variables tracked covered three key domains of the research question: (1) psychological and physiological responses (feel), (2) neurocognitive responses (think), and (3) design originality and incorporation of biophilia (design). Results showed that the biophilic auditory experience induced higher physiological arousal during and after exposure, while the visual and multisensory conditions presented evidence of increased neural efficiency. The biophilic conditions assisted in restoring cognitive resources and improved prefrontal cortical functional connectivity, specifically within main hubs of the Default Mode Network (DMN). However, better engagement of the DMN did not result in more original design products. No significant differences were found for exploration of the design space across conditions. Interestingly, the visual group incorporated significantly more biophilic design patterns, such as "Visual Connection with Nature" and "Presence of Water", in their design concepts. This finding suggests a potential priming effect, where exposure to biophilic stimuli influenced designers' choices towards more nature-connected ideas. The study here presented contributes to the understanding of biophilic restorative experiences' nuanced effects on physiology, neurocognition, and design cognition. Accessibility and availability of the interventions tested affords readily replication of the experiment design and application of findings to the general public. / Doctor of Philosophy / This dissertation explores how exposure to simulated nature experiences through different senses affects how engineers feel, think, and design. Two main environmental psychology theories propose that nature experiences can aid in the recovery from stressful states and mental fatigue. The Kaplans' Attention Restoration Theory suggests that looking at nature can help the brain recover from overuse by allowing it to restore attentional resources. Roger Ulrich's Stress Reduction Theory proposes that nature experiences can reduce stress by calming the body and the mind. While previous studies have mainly explored the effects of exposure to nature through visual experiences, the study presented here examines the effects of exposure to nature-based sounds (birdsong and water sounds), as well as exposure to the combination of sounds and visuals (indoor plants, nature-inspired art, and daylight). Additionally, it investigates how the potential benefits to the brain and mind influence performance in real-world tasks like designing. To explore these effects, 154 engineering students were randomly assigned to different groups and exposed to nature sounds, nature visuals, or a combination of both, after being induced to a stressful state. After the exposure period, participants were given an open-ended design task. Throughout the experiment, participants' bodily responses were tracked by a wrist-worn device and participants' brain activity was tracked by a brain-imaging headset. Design concepts produced in the design task were assessed for originality and for the incorporation of nature-inspired ideas. Results showed that listening to nature sounds increased arousal of the body both during and after the exposure period. Visual, as well as combined auditory and visual exposure improved brain efficiency. All nature experiences helped restore mental resources and improved brain connectivity, particularly in areas associated with mind wandering. Although better brain connectivity did not result in more original design concepts, interestingly, participants in the visual exposure group incorporated more nature-related features, like bodies of water and natural views, into their designs. This finding suggests that seeing nature might inspire more nature-connected design ideas. This study enhances our understanding of how nature experiences affect the body, brain, and mind. The interventions tested can be easily replicated and applied in everyday settings so that anyone can benefit off of their outcomes.