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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
31

Aspekte der Positionierung und Dosisapplikation in der stereotaktisch geführten intra- und extrakranialen Strahlentherapie

Ahlswede, Julia 01 November 2005 (has links)
Stereotaktische Strahlenchirurgie und -therapie (SRS/SRT) weisen sich durch sehr konformale und hochpräzise Dosisverteilungen aus. Im Kopfbereich ist SRS/SRT eine etablierte Behandlungsmethode. Um diese Technik in anderen Körperregionen anwenden zu können, wurden verschiedene Positionierungs- und Fixierungsmethoden, sowie der Einsatz von 9 verschiedene Bestrahlungstechniken untersucht. Es wurde auch die Genauigkeit von 2 Dosisalgorithmen evaluiert. Jeweils eine thermoplastische Maske für den Kopf- und den Kopf-Hals-Bereich, sowie ein Doppelvakuumsystem für extrakraniale Regionen wurden untersucht. Die Kopfmaske erreichte im Durchschnitt eine Genauigkeit von 1,8mm (Fehler 0,9mm), mit einem Oberkiefersupport auf 0,96mm +/- 0,25mm. Die Kopf-Hals-Maske zeigte mit 0,7mm +/- 0,4mm, dass ihre Verwendung in der SRS/SRT möglich ist. Für die Genauigkeit des Doppelvakuums wurde durchschnittlich 7,0mm +/-3,5mm ermittelt. Relativ zum Vakuumkissen wurde eine Genauigkeit von 1,6mm +/- 1,87mm gemessen. Evaluierungsmethoden waren IR-Marker, die mittels Zahnabdruck am Patienten fixiert wurden und fusionierte Wiederholungs-CTs, in denen die Verschiebung von Landmarken am Positionierungssystem und im Patienten vermessen wurden. Bei den Bestrahlungstechniken sind 3 Techniken durch gute Ergebnisse aufgefallen. Stehfeldtechnik, dynamischer Arc und IMRT zeigten mit einem 3mm-mMLC hohe Konformität und Homogenität auf. Die ersten beiden Techniken erreichten steile Dosisgradienten, wohingegen die IMRT bei komplexen Zielgebieten und nahen Risikostrukturen auffiel und immer die geforderte 90%-Umschließende erreichte. Die Verifizierung der Dosisalgorithmen erfolgte anhand von Filmen. 8 Pläne wurden jeweils auf einem Film in Isozentrumsebene abgebildet und ein Vergleich mit der berechneten Dosis von Clarkson- und Pencil-Beam-Algorithmus mit Hilfe der Gamma-Evaluation durchgeführt. Beide Algorithmen sind für die SRS/SRT geeignet, der Pencil-Beam-Algorithmus zusätzlich für die IMRT verwendbar. / Stereotactic radiation surgery and therapy (SRS/SRT) are able to deliver conformal and precise dose distributions. For brain lesions SRS/SRT is a well-established technique. Its success increases interest to use it in other areas of the body. For this, evaluation of different patient positioning and treatment techniques, as well as dose algorithms have been performed. As patient fixation and positioning systems, 2 thermoplastic masks were evaluated for lesions located in the brain and the head and neck. In addition a double vacuum system for extra cranial treatments was used. The precision for the head mask was on average 1,8mm +/- 0,9mm, with an upper jaw support 0,9mm +/- 0,25mm. The head and neck mask realized a reproducibility of 0,7mm +/- 0,4mm and proved its use for SRS/SRT. For extra cranial positioning an average lesion misplacement of 7,0 mm +/-3,5 mm was measured. Relative to the vacuum cushion the accuracy was measured to be 1,6mm +/- 1,9mm. Infrared reflecting marker fixed precisely (+/- 0,6mm) with a dental impression and repeated CTs fused and landmark evaluated were successfully used to evaluate the patient fixation and positioning devices. 3 out of 9 treatment techniques had outstanding results. Static beams, dynamic arcs and IMRT all performed with a 3mm-mMLC showed a high conformity and homogeneity. The first two showed steep dose gradients and the later coped best with complex target shapes, close-by risk organs, and achieving 90% dose coverage. Verification of 2 algorithms was established with film. 8 plans were irradiated on film at isocenter and compared to calculations with Clarkson and pencil beam algorithm. Final evaluation was done using Gamma evaluation. Both algorithms showed their ability for SRS/SRT. The pencil beam algorithm is also capable of calculating IMRT plans. Summing the results the finding show that the use of some of the SRS-SRT techniques used for the head may be transferred for the use in extra cranial areas.
32

Návrh podnikového finančního plánu / A Draft of a Corporate Financial Plan

Seidl, Jakub January 2020 (has links)
This master’s thesis is focused on a Draft of a Corporate Financial Plan for industrial company P-D Refractories CZ a.s. for years 2019 to 2022. First chapter of this master’s thesis is oriented in goals, methods and approaches of this thesis. Next part is aiming at theoretical solution for financial planning. Third chapter contains information about analyzed company, application of selected methods of strategic analysis and financial analysis including evaluation of the state of company and detection of potential deficiencies. Last chapter of this thesis is focused on suggestion, formation and evaluation of the financial plan for P-D Refractories CZ a.s. for next four years.
33

Návrh podnikového finančního plánu / A Draft of a Corporate Financial Plan

Říhová, Kristýna January 2021 (has links)
This thesis deals with the proposal of the financial plan for COM Group, a.s. company which operates in ICT industry. First part of this thesis aims for its theoretical background, which is cornerstone for the development of proposal of the financial plan. The next chapter is dealing with an introduction of picked company and its subsequent process of the strategic and financial analysis of the picked company. Conclusively, there is processed financial plan for the period 2020-2023 and its evaluation.
34

Návrh podnikového finančního plánu / A Draft of a Corporate Financial Plan

Křenková, Jana January 2018 (has links)
This master’s thesis deals with topic of financial planning of the company. The first part of the thesis describes the theoretical background, whose knowledge is necessary for drawing up the financial plan. Subsequently, the thesis is focused on introducing the selected company Then the necessary analyzes, strategic and financial, will be carried out to evaluate the current situation of the company, which serves as a basis for the financial plan itself. That will soon be drawn up for the next three marketing years. The final part of the thesis includes evaluation and feedback of this financial plan.
35

Návrh podnikového finančního plánu / Proposal of the Company's Financial Plan

Novák, Jindřich January 2010 (has links)
This thesis with title „Proposal of the Company's Financial Plan“ consists of theoretical and practical parts. Theoretical part deals with theoretical ways out of financial planning. In the practical part there are performed the analyses of contemporary state of company. Afterwards there is the financial plan alone made-up for the years 2009 – 2011. The end of my practical part is formed by evaluation of created financial plans.
36

Návrh podnikového finančního plánu / Proposal of the Company's Financial Plan

Přibyl, Pavel January 2011 (has links)
This thesis with title „Proposal of the Company's Financial Plan“ consits of two basic part. Theoretical part deals with theoretical ways out of financial planning. In the practical part there are performed the analyses of contemporary state of the company STABILA ČR, s. r. o. Afterwards there is the financial plan alone made-up for the years 2011 – 2013. The end of this thesis is formed by evaluation of created financial plans.
37

Návrh podnikového finančního plánu / Proposal of the Company's Financial Plan

Blažková, Jana January 2013 (has links)
Diploma's thesis deals with problems of the financial planning business. The theoretical part of the thesis focuses on the theoretical foundations of financial planning. The second part of the thesis analyses contemporary state of the company. Subsequently is drew up the financial plan for the years 2012-2014. The conclusion includes the evaluation of the compiled financial plans.
38

Návrh podnikového finančního plánu / A Draft of a Corporate Financial Plan

Reschowský, David January 2016 (has links)
The diploma thesis focuses on a corporate financial plan proposal, and consists of theoretical and practical part. The theoretical part deals with theoretical solutions of financial planning. The practial part contains analyzes showing the current state of the corporation. Further, a financial plan for 2016-2019 year period is compiled. The thesis concludes with an evaluation and examination of compiled financial plans.
39

Návrh podnikového finančního plánu / Proposal of the Company's Financial Plan

Pešová, Veronika January 2010 (has links)
This thesis consists of three main parts. The first one contains theoretical data for financial planning. It is focused on principles and methods of financial planning, on creation of short – term and long – term financial plan and its following control. In the second part there is implementation of evaluation of contemporary situation in chosen company and financial analysis that act as a basis for formation of financial plan. The practical part contains financial plan design of ABC, s.r.o. company.

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