NDLTD Global ETD Search
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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

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Spelling suggestions: "subject:"plasmacytomas"" "subject:"plasmacytoma""

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c-Myc- driven nuclear repositioning of chromosome 11 in mouse plasmacytomas and its clinical significance

Sunpaweravong, Patrapim 27 January 2017 (has links)
Overall, this study enhances our understanding of the role of c-Myc activation in chromosome 11 repositioning in mouse PreB v-abl/myc cells and a possible interaction between telomeres, TRF2, and lamin A/C underlying this phenomenon. Additionally, the importance of human 17q25.3 is confirmed as a potential region involved in NSCLC tumorigenesis. A utilizationof the 3D telomeric organization profiles is demonstrated a tendency to categorize NSCLC patients into different prognostic subgroups, underscoring a potential future value of its clinical application. / February 2017
c-Myc
Repositioning
Mouse chromosome 11
Plasmacytomas
Non-small cell lung cancer
Three-dimensional
Telomeres
Nuclear matrix
TRF2
Lamin A/C

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