The work described in this thesis is concerned with the development and application of real-time photo-CIDNP (Chemically Induced Dynamic Nuclear Polarisation) to the study of protein structure and folding. Chapters 1 and 2 introduce the protein folding problem, and its study by NMR, then go on to elucidate the mechanisms behind the photo-CIDNP phenomenon. Chapter 3 applies photo-CIDNP spectroscopy to the study of a small cytochrome protein. The difficulties of performing these experiments on chromophore-containing proteins are discussed. Chapter 4 begins with the development of a rapid mixing device for use in real-time NMR and CIDNP studies. Experiments used to characterise the device are presented. This chapter then goes on to describe CIDNP pulse labelling experiments, used to investigate the surface structure of some molten globule states of two a-lactalbumins. This chapter concludes with an application of the rapid mixing device to the real-time refolding of hen egg white lysozyme. Chapter 5 extends the work of the previous chapter, studying the real-time refolding of bovine pancreatic ribonuclease A. Refolding studies are performed from different denaturing conditions, and the effects of sample heating during the real-time CIDNP experiment are discussed. Chapter 6 describes the use of illumination during an NMR experiment to study the conformational changes in a plant blue light receptor protein, phototropin. The structural changes are characterised with 2-dimensional NMR spectroscopy and photo-CIDNP. The kinetics of the ground state recovery are also investigated by real-time NMR spectroscopy. Chapter 7 uses calculated hyperfine coupling constants and a radical pair diffusion model from the literature to simulate the nuclear polarisation obtained for the amino acid tryptophan. Comparisons are made between theory and experiment. Chapter 8 describes the structural characterisation of a homologous series of de novo peptides, designed for subsequent use in EPR experiments when derivatised with a suitable spin label.

A complete renormalization scheme for the Glashow-Salam-Weinberg model is presented. As input parameters the scheme uses the fine structure constant, α, the muon decay constant, G_μ and the Z° mass, M_Z which are known or will be measured to high accuracy in the near future. These are used along with the Higgs and fermion masses to obtain the W mass, M_W. The full one-loop weak radiative corrections to the longitudinal polarization asymmetry, A_pol, and the forward-backward asymmetry, A_fb, in e⁺e^- → μ⁺μ^- are then calculated both on and off resonance. On resonance the results depend extremely sensitively on the Z mass, M_Z, and to a lesser extent on the top quark mass, m_t, and the Higgs mass, M_H, showing that this is a good place to test the standard model at the one loop level. The results are displayed over the full range of the parameters allowed by experimental and theoretical constraints. It is suggested that sufficiently accurate experiments may be able to set an upper bound on one of m_t or M_H if the other is known. It is noted that on resonance A_pol is only weakly dependent on the beam pipe and on the nature of the outgoing fermions. Comparison is made with other calculations of A_fb and the agreement is found to be good. The predictions are also compared with measurements of A_fb off resonance and are found in all cases to lie within the experimental errors. Previous analyses that indicated a possible discrepancy are shown to be incorrect.

We compute the anomalous dimension (gamma)(n) and (gamma)(,ns)(n) needed in the evaluation of the polarized structure function G(,1)(q('2)) in electron-proton scattering, up to and including the order g('4) contributions in the minimal subtraction scheme in perturbative QCD. Both the analytic expression and the numerical result for (gamma)(n) and (gamma)(,ns)(n) with n = 2, 4, 6,..., 20 are obtained. We also evaluate the second moment of flavor singlet and the flavor non-singlet part of G(,1)(q('2)) in QCD, with 4 and 6 flavors with the Wilson coefficients left as unknowns.

Thesis (Ph. D.)--Virginia Polytechnic Institute and State University, 1992. / Vita. Abstract. Includes bibliographical references (leaves 115-118). Also available via the Internet.

Thesis (M.S.)--Virginia Polytechnic Institute and State University, 1992. / Vita. Abstract. Includes bibliographical references (leaves 137-145). Also available via the Internet.

Thesis (Ph.D.)--University of California, Berkeley, 1962. / "UC-34 Physics" -t.p. "TID-4500 (17th Ed.)" -t.p. Includes bibliographical references (p. 65-66).

Thesis--University of California, Berkeley, 1959. / "Physics and Mathematics" -t.p. Includes bibliographical references (p. 125-126).

Thesis (Ph. D.)--University of California, Riverside, 2010. / Includes abstract. Title from first page of PDF file (viewed May 18, 2010). Includes bibliographical references. Issued in print and online. Available via ProQuest Digital Dissertations.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1970. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliography.

Thesis (M.S.)--Miami University, Dept. of Physics, 2007. / Title from first page of PDF document. Includes bibliographical references (p. 49-50).