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New Porphyrin Architectures for Biomedical ApplicationsLovell, Jonathan 31 August 2012 (has links)
From the green chlorophyll in plants and algae that we depend upon to transform sunlight into useful energy, to the red heme that carries oxygen to the cells in our bodies, porphyrins are the colors of life. It is not surprising then, that porphyrins have been actively interrogated as tools for diverse applications to improve biotechnology and medicine. With the goal of improving cancer therapy and diagnosis in mind, this thesis examines new modular porphyrin architectures. These constructs have interesting properties that extend beyond their originally intended use as phototherapeutic agents. In Chapter 1, a comprehensive background on
porphyrin-based activatable photosensitizers is presented. In Chapter 2, porphyrin singlet
oxygen and fluorescence quenching is examined in a model system with respect to Förster theory. Chapter 3 examines a new DNA responsive molecular beacon that was quenched using multiple quenching moieties and its application for nanoparticle aggregation. Chapter 4 describes extremely self-quenched nanovesicles formed from porphyrin-lipid conjugates that displayed a number of desirable properties for nanomedicine applications. Chapter 5 presents a brief discussion and some potential future directions of the research. It is my hope that the data presented in this thesis set the stage for new porphyrin-based approaches to make a translational impact in the battle against cancer and other diseases.
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Asymmetric organic oxidation by chiral ruthenium complexes containing D2 and D4 symmetric porphyrinato ligandsZhang, Rui, January 2000 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2001. / Includes bibliographical references (leaves 197-212).
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Sapphyrins aggregation and anion binding behavior in polar, protic media /Davis, Julian Murray. January 2001 (has links)
Thesis (Ph. D.)--University of Texas at Austin, 2001. / Vita. Includes bibliographical references. Available also from UMI Company.
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Complexes of iminato, nitrido, imido, and hydrazido ruthenium of osmium porphyrins /Leung, Ka-yan, Sarana. January 2002 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2002. / Includes bibliographical references.
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Transition metal complexes of expanded porphyrinsTomat, Elisa 28 August 2008 (has links)
Not available / text
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Sapphyrins : aggregation and anion binding behavior in polar, protic mediaDavis, Julian Murray 09 March 2011 (has links)
Not available / text
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Transition metal complexes of expanded porphyrinsTomat, Elisa, 1977- 18 August 2011 (has links)
Not available / text
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THE REDUCTION MECHANISMS OF WATER SOLUBLE PORPHYRINSNeri, Bruce Philip, 1946- January 1972 (has links)
No description available.
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Porphyrin-based multicomponent supramolecular assembliesAlemán-García, Miguel Angel January 2012 (has links)
No description available.
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Resonance raman studies of ligand binding in cobalt (II) "picket fence" porphyrin and iron (III) octaethylporphyrinMackin, Helen Catherine 08 1900 (has links)
No description available.
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