The most important aim of pre-positioning is to reduce the delivery lead time with eliminating the procurement stage by positioning items closer to the disaster area. The last 30 years&rsquo / data is used to designate the disaster trends / EM-DAT database is used to acquire the necessary data which includes the disaster locations, type of disasters and number of people affected. Also the most recent four years&rsquo / data is used for verification of the results. Locations of the optimal warehouses for pre-positioning are determined considering the generated emergency response scenarios. When we pursue this exploration, besides determining the optimal pre-positioning locations given by CARE International, we also determined where the natural disaster trend drifts towards.Therefore, this research tries to find an answer whether the disaster trends should be considered to determine the location of the pre-positioned items or not.