Yes / This study aimed to explore more on contributing factors and prevention of overweight and obesity among Pacific islanders. Methods: Using Cochrane library guideline, four electronic databases, PubMed, Embase, Scopus and CINAHL, were systematically searched from 2010 to 2020. Search strategy included key concepts, free text terms, and database-controlled vocabulary terms to identify articles on determinants and preventative strategies of overweight and obesity in the Pacific countries. A data extraction sheet was developed to extract relevant information required for analysis and theme development for this study. Results: A total of 22 articles were summarized and categorized. Determinants of overweight and obesity identified two themes: environmental related factors 13.6% (3/22) and sociocultural related factors 27.3% (6/22). The preventative strategies of overweight and obesity was categorized into behavioural change 22.7% (5/22), school-related 18.2% (4/22), and policies 50% (11/22). The quality assessment of articles showed “Good” 68.2% (15/22), and “Fair” 31.8% (7/22). Conclusion: This study highlighted two contributing, non-medication factors affecting overweight and obesity are both environmental and socio-cultural issues. Overweight and obesity preventative strategies identified in the Pacific context considered behavioural change, knowledge enhancement, and policy development. Further research should aim at exploring the current preventative strategies in-depth, to appreciate the most feasible and recommended preventative approach within the Pacific society.