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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

AvaliaÃÃo da glutamina sintetase e da concentraÃÃo da glutamina no terÃo final da gestaÃÃo e na lactaÃÃo de camundongos fÃmeas e matrizes suÃnas primÃparas / Evaluation of the glutamina sintetase and the concentration of the glutamina in terÃo final of the gestation and in the lactation of female and first mice suÃnas primÃparas

Helena EmÃlia Cavalcanti da Costa Cordeiro Manso 01 December 2006 (has links)
nÃo hà / A glutamina (Gln), aminoÃcido por ser nÃo-essencial, nÃo à tradicionalmente incluÃdo nas raÃÃes animais. As propriedades metabÃlicas da Gln fazem dela um aminoÃcido condicionalmente essencial em perÃodos de estresse e catabolismo, quando o organismo nÃo tem a habilidade de suprir em tempo hÃbil sua demanda nutricional. A presente pesquisa foi dividida em 2 partes, a primeira delas teve por objetivo de avaliar o metabolismo da glutamina (Gln) e da glutamina sintetase (GS) no perÃodo lactacional de camundongos fÃmeas primÃparas, a segunda parte teve o objetivo de avaliar os efeitos da suplementaÃÃo da Gln na dieta, fornecida em 2 formas, uma delas, pura (L-glutamina) e uma outra associada ao Ãcido glutÃmico (AminoGut Ajinomoto) para matrizes suÃnas primÃparas. No primeiro experimento caracterizou-se a importÃncia da GS e da Gln e evidenciou-se o seu importante papel no metabolismo, quando o animal se encontrava em catabolismo. No segundo experimento, a glutamina mais uma vez demonstrou sua importÃncia na manutenÃÃo da higidez da matriz. Mais estudos devem ser feitos no intuito de estabelecer nÃveis adequados de suplementaÃÃo e de avaliar a subsequente performance reprodutiva de matrizes suÃnas assim como o desempenho dos leitÃes apÃs o desmame / The glutamine (Gln), a non-essential amino acid, normally it isnât included in the animal feed. The metabolic properties of glutamine made it an essential conditionally amino acid during stress and catabolism, when the body has no ability to attend the nutritional requirements. The present research was divided in two parts; the first one had the objective to characterize the glutamine (Gln) and the glutamine synthetase (GS) during lactation of primiparous mice and the second one, the aim was to evaluate the effects of glutamine supplementation, given in two forms, pure (L-glutamine) and in association with glutamic acid (AminoGut by Ajinomoto) for primiparous gilts. In the first experiment was characterized the importance of GS and Gln, and the important role on the animal metabolism during a catabolism. In the second experiment was demonstrated the importance of Gln to maintain the gilt health. More studies should have to establish the adequate level of Gln supplementation and to evaluate the reproductive performance of gilts as well as the piglets development after weaning.

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