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DIII domain of calpain 10 and Cpl towards an understanding of calpain 10 function /Huang, Xinhua. January 2003 (has links)
Thesis (Ph. D.)--Medical College of Ohio, 2003. / "In partial fulfillment of the requirements for the degree of Doctor of Philosophy in Medical Sciences." Major advisor: Ronald Mellgren. Includes abstract. Document formatted into pages: iv, 126 p. Title from title page of PDF document. Includes bibliographical references (p. 92-124).
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Giardia CWP2 : determining its immunogenic[i]ty and its potential as a candidate for vaccine against giardiasisLarocque, Renée, 1975- January 2000 (has links)
In this study, we determined the immunogenicity of CWP2 and its potential as a vaccine candidate against giardiasis. CWP2 was expressed as a recombinant protein with an hexa-histidine affinity tag and was isolated from inclusion bodies. When BALB/c mice were immunized with CWP2, a specific IgA was detected in the feces. When mice were immunized with CWP2 + cholera toxin, as an adjuvant, IgA in the feces, and IgA, IgG1, and IgG2a in the serum, all specific to CWP2, were detected. Also, CD-1 mice were infected with G. muris and presence of specific IgA antibodies to CWP2 were detected in the feces. This result indicated that CWP2 was recognized by the immune system in a natural infection. IL-4 and IL-5 were released from Peyer's patches (PP) and mesenteric lymph nodes (MLN) cells when stimulated with concanavalin A. In spleen cells, IFN-gamma, IL-4, and IL-5 were released when stimulated with concanavalin A. However, in PP, MLN and spleen cells, the levels of cytokines were barely detectable when stimulated with CWP2. The presence of IgG2a (Th1), IgA and IgG1 (Th2) as the production of IFN-gamma (Th1), IL-4 and IL-5 (Th2) confirmed that CWP2, when presented orally to mice, stimulates both a Th1 and Th2 type immune response, locally and systemically.
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Giardia CWP2 : determining its immunogenic[i]ty and its potential as a candidate for vaccine against giardiasisLarocque, Renée, 1975- January 2000 (has links)
No description available.
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Investigation of a method to reduce false-positive equine protozoal myeloencephalitis test results titleHeskett, Katherine A., January 2004 (has links)
Thesis (M.S.)--University of Florida, 2004. / Typescript. Title from title page of source document. Document formatted into pages; contains 79 pages. Includes Vita. Includes bibliographical references.
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Identification of new proteins and biological processes in the apicomplexan Toxoplasma gondii /c Silvia Botero-Kleiven.Botero-Kleiven, Silvia, January 2006 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 3 uppsatser.
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Protein trafficking and 4.1R relocalization in Plasmodium falciparum-infected erythrocytesParish, Lindsay A. January 2009 (has links) (PDF)
Thesis (Ph.D.)--University of Alabama at Birmingham, 2009. / Title from PDF title page (viewed on Sept. 9, 2009). Includes bibliographical references.
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Structural and biochemical studies of trypanosomatid drug target proteins /Choe, Jungwoo. January 2003 (has links)
Thesis (Ph. D.)--University of Washington, 2003. / Vita. Includes bibliographical references (leaves 129-143).
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Parasite signalling and host responses in experimental and human African trypanosomiasis /Hamadien, Maha, January 2002 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2002. / Härtill 4 uppsatser.
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Immunodominant proteins in Giardia lamblia /Weiland, Malin, January 2004 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 4 uppsatser.
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Variable surface molecules of the Plasmodium falciparum infected erythrocyte and merozoite /Haeggström, Malin, January 2006 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 4 uppsatser.
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