Many important tasks in finance often rely on complex and time-consuming computations. The rapid development of quantum technology has raised the question of whether quantum computing can be used to solve these tasks more efficiently than classical computing. This thesis studies the potential use of quantum computing in finance by solving differently-sized problem instances of the mean-variance portfolio selection model using commercially available quantum resources. The experiments employ gate-based quantum computers and quantum annealing, the two main technologies for realizing a quantum computer. To solve the mean-variance optimization problem on gate-based quantum computers, the model was formulated as a quadratic unconstrained binary optimization (QUBO) problem, which was then used as input to quantum resources available on the largest quantum computing as a service (QCaaS) platforms, IBM Quantum Lab, Microsoft Azure Quantum and Amazon Braket. To solve the problem using quantum annealing, a hybrid quantum-classical solver available on the service D-Wave Leap was employed, which takes as input the mean-variance model’s constrained quadratic form. The problem instances were also solved classically on the model’s QUBO form, where the results acted as benchmarks for the performances of the quantum resources. The results were evaluated based on three performance metrics: time-to-solve, solution quality, and cost-to-solve. The findings indicate that gate-based quantum computers are not yet mature enough to consistently find optimal solutions, with the computation times being long and costly as well. Moreover, the use of gate-based quantum computers was not trouble-free, with the majority of quantum computers failing to even complete the jobs. Quantum annealing, on the other hand, demonstrated greater maturity, with the hybrid solver being capable of fast and accurate optimization, even for very large problem instances. The results from using the hybrid solver justify further research into quantum annealing, to better understand the capabilities and limitations of the technology. The results also indicate that quantum annealing has reached a level of maturity where it has the potential to make a significant impact on financial institutions, creating value that cannot be obtained by using classical computing.