- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
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Severe Bactrim-Induced Neutropenia With Reversal of CD4<sup>+</sup>/CD8<sup>+</sup> Lymphocyte Ratio: Response to Recombinant Human Granulocyte-Colony Stimulating Factor (R-metHUG-CSF)Krishnan, K., Krishnaswamy, G. 18 July 1998 (has links)
A patient presented with severe bactrim-induced neutropenia with a reversed CD4+/CD8+ lymphocyte ratio. R-metHUG-CSF at 300 μg daily produced a dramatic neutrophil response and the therapy was discontinued after 2 weeks.
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Successful Treatment of Autoimmune Neutropenia With Recombinant Human Granulocyte-Colony Stimulating Factor (R-metHuG-CSF)Krishnan, K., Ross, C. W., Bockenstedt, P. L., Adams, P. T. 01 January 1997 (has links)
Autoimmune neutropenia (AIN) is characterized by antibody mediated peripheral destruction of neutrophils. Since there is no effective treatment, antibiotics have to be used frequently for recurrent infections. Five selected patients with serologically proven AIN were treated with r-metHuG- CSF at 5-8 μg/kg body weight (300-480 μg) daily: the dose and frequency of r-metHuG-CSF was reduced after neutrophil counts above 1.0 x 109/l were obtained. R-metHuG-CSF is effective in AIN and causes a sustained rise in ANC which can he maintained on a low dose administered twice or thrice weekly.
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