Thesis (M.S.)--Oregon State University, 2010. / Printout. Includes bibliographical references. Also available on the World Wide Web.

Thesis (M.S.)--Oregon State University, 2009. / Printout. Includes bibliographical references (leaves 104-112). Also available on the World Wide Web.

Thesis (M.S.)--Montana State University, 2004. / Title from PDF title page (viewed Jan. 6, 2005). Includes bibliographical references (p. 52-56).

The influence of alfalfa fiber level 28, 54 and 74% in diets on the proximate compositions, pH and water-holding capacity of raw and cooked rabbit meat were investigated. Preslaughter live weight, percent dress weight and percent abdominal fat of rabbits fed 54% alfalfa fiber diet were significantly higher and total moisture content in raw rabbit meat was significantly less than those of rabbit groups fed 28 and 74% alfalfa fiber diets. The cooked meat from rabbit fed 54% alfalfa fiber diet had a lower protein content and total cooking losses as compared to the other two alfalfa fiber diets. From the results, the 54% was considered as the optimum alfalfa fiber level for rabbits to achieve optimum growth and to produce good quality meat. Cooking the rabbit meat increased pH, total protein, total lipids, and total cholesterol. However, on a dry weight basis, the total cholesterol content decreased which was caused by heat degradation. Alfalfa fiber level and the sex factor interaction effect was observed on the total cholesterol content on dry weight basis, and calcium on wet weight basis in raw meat. On wet weight basis, rabbit meat from all three groups fed alfalfa fiber diets contained an average of 74% total moisture, 21.95% total protein, 13.234 mg/100g calcium, 393 mg/100g potassium, 3.57% total lipids, and 74.93 mg/100g total cholesterol. Compared with other edible meat such as beef and pork, rabbit meat is a good source of edible meat. / Graduation date: 1982

Thesis (Ph. D., Natural Resources)--University of Idaho, May 2008. / Major professor: Janet L. Rachlow. Includes bibliographical references. Also available online (PDF file) by subscription or by purchasing the individual file.

Thesis (Ph. D., Natural Resources)--University of Idaho, December 2007. / Major professor: Janet L. Rachlow. Includes bibliographical references. Also available online (PDF file) by subscription or by purchasing the individual file.

No description available.

This study sought to determine if the generalization gradient obtained along the frequency dimension of acoustic clicks would be similar for a group of rabbits simultaneously conditioned to stimuli consisting of 15 pulses of brain stimulation per second and 25 clicks per second, and a group of rabbits conditioned to stimuli consisting of 15 and 25 acoustic clicks per second. A summated generalization gradient along the frequency dimension of acoustic clicks was obtained from rabbits conditioned to ESB and acoustic clicks if the electrode tips were located in the medial geniculate body. If the electrode tips were located in nonauditory brain structures (e.g., optic tract, lateral geniculate body, midbrain reticular formation), the generalization gradient obtained along the frequency dimension of acoustic clicks resembled one obtained from a group of rabbits initially conditioned to a stimulus consisting of 25 acoustic clicks per second. The results are discussed in terms of providing evidence for a frequency theory of learning and questioning the usefulness of a "labeled lines" code for carrying information within the central nervous system.

Thesis (Ph.D. 1974) -- University of Adelaide, Dept. of Zoology, 1974.

There is a need to develop a range different VLP for use as nanoscale templates and vaccines. The aim of this research was to develop RHDV VLP as a versatile vaccine delivery system easily modified for use against a wide range of different diseases. Production of Rabbit haemorrhagic disease virus (RHDV) capsid protein in a baculovirus system led to the self-assembly of Virus-like Particles (VLP) that could be purified to greater than 99% purity using simple methods. The capsid gene, vp60, can be manipulated genetically to incorporate immunogenic peptide sequences or a functional DNA-binding site. Fusion of these small epitopes to VP60 was well tolerated, forming VLP and greatly enhanced the presentation of peptide to, and activation of CD4+ T helper cell hybridoma. To avoid constraints imposed on chimeric VLP and dramatically increase the versatility of RHDV VLP, rapid conjugation of antigen was carried out, employing the hetero-bifunctional chemical linker, sulpho-SMCC. Incorporation of sulfhydral groups by design or treatment with SATA allowed for great versatility, in turn enabling many diverse peptides and proteins to be conjugated to VLP. RHDV VLP and consequently the conjugated GFP antigen were efficiently taken up by DC with more than 85% of DC positive for GFP by flow cytometry. This was also visualised by confocal microscopy and electron microscopy of both gold- labelled VLP and conjugated antigen. RHDV VLP conjugate was shown to induce the significant up regulation of the activation markers CD40, CD80, CD86 and MHC class II on the surface of dendritic cells (DC). As well, DC pulsed with RHDV VLP/OVA effectively presented OVA to both CD4+ and CD8+ T cells transgenic for respective peptide-specific T cell receptors, eliciting a greater proliferative response in both T cell subsets than antigen delivered alone. The surface accessibility of peptides on VLP was demonstrated, while administration of VLP/Ovalbumin (OVA) conjugate in mice was shown to evoke very high titre antibody responses specific for conjugated antigen. VLP/OVA conjugates were also shown to induce IFN-γ production and OVA-specific cytotoxic killing in vivo, of up to 80% of fluorescently labelled, adoptively transferred target cells. No distinguishable cytotoxicity was detected in unimmunised control mice. This assay was also used to demonstrate the necessity for antigen to be conjugated to VLP, as antigen mixed with VLP induced only sub-optimal killing. To investigate the anti-tumour effects, mice vaccinated with VLP conjugated to OVA protein, CD4+ or CD8+ T cell OVA epitopes were inoculated with B16- OVA tumour cells and monitored for tumour growth. Untreated control mice had to be sacrificed by day 19, while mice immunised with either VLP/OVA or VLP conjugated with both CD4+ and CD8+ OVA epitopes, showed a significant delay in tumour growth (P = 0.0002), with one mouse remaining free of palpable tumour until day 92. These results show that RHDV VLP can be easily produced and purified and demonstrate the versatility of this RHDV capsid. Rapid conjugation techniques allowed the modification of VLP with both peptide and protein rendered these antigens highly immunogenic, stimulating both humoral and cell-mediated immunity targeted against conjugated antigens of choice. The versatility and immune stimulating properties of RHDV VLP provides a molecular tool with almost limitless applications within the fields of nanotechnology and immunology.