Thesis (M.D.)--University of Maryland, 1814. / Includes bibliographical references. Microform version available in the Readex Early American Imprints series.

Photocopy of typescript. / Digitized by Kansas Correctional Industries

Thesis (M.Sc.) (Microbiology)-University of Pretoria, 2005. / Abstract in English. Includes bibliography. Available on the internet via the World Wide Web.

No description available.

Thesis (M.S.)--University of Wisconsin. / eContent provider-neutral record in process. Description based on print version record.

The purpose of these investigations was to isolate and purify the largest of several antigens demonstrable in rabies-infected suckling mouse brains. The biochemical and biophysical properties of the antigen were studied with a view to elucidating its contribution to the intracellular synthesis and the structure of the virus particles. Extracts of normal and infected suckling mouse brains were purified by precipitation at pH 4.5 and freed of the smaller antigens by centrifugation prior to digestion with RNAase, DNAase and trypsin. The large antigen was purified by enzyme treatment, preparative ultracentrifugation, exclusion chroma tography and gradient centrifugation and appeared as rings varying in diameter between 8 and 12 mμ when examined by electron microscopy. Methods for the chemical estimation of pentose, deoxypentose and nitrogen were modified to meet the requirements of this investigation, and these techniques were used to determine the composition of the purified antigen. The antigen is a ribonucleoprotein, and found to be resistant to RNAase, DNAase, trypsin and chymotrypsin. A purified solution of the antigen contained 7.3μg RNA/ml., 11.4μg protein/ml and probably a trace of DNA. The success of this programme has resulted in the accumulation of certain original information which has been used in clari£ying the nature and structure of the largest soluble antigen.

Thesis (MSc. (Paraclinical Sciences, Veterinary Science)--University of Pretoria, 2009. / Includes bibliographical references. Also available in print format.

Thesis (M.S.)--Ohio State University, 2005. / Includes bibliographical references (leaves 86-91). Available online via OhioLINK's ETD Center

Digitized by Kansas State University Libraries

Striped skunks (Mephitis mephitis) are a rabies vector in Texas and efforts are underway to develop an oral rabies vaccination program for skunks. To better understand some of the components necessary, I studied the habitat preferences and home range of skunks, an alternative skunk capture method, and surveyed the knowledge base of medical providers practicing across the state. I radiocollared 99 skunks from the Houston, Texas metropolitan area and monitored skunk movements from March 2004–June 2006. To accelerate progress of this study, I captured 93 of 99 skunks using a dip net. Dip netting allowed for an effective collection alternative to cage trapping. Movement data indicated a strong preference for short grass areas (82%), however, habitat use changed to remote, brushy areas when temperatures were ≤7C. Habitat use during the year was different (P = 0.001), with December 2004, January 2005, and February 2005 significantly (P = 0.001) different from one another. Additionally, habitat use during December 2005, February 2006, and March 2006 were significantly different (P = 0.045, P =0.098, and P =0.003, respectively). Data from 20 skunks, covering multiple seasons, were analyzed for home range use. I found male home range use averaged 255 ha (217–345), while females averaged 126 ha (60–218). Male range use was significantly larger than females (P = 0.005). No significant seasonal movements were observed. Lastly, I conducted a survey of 297 Texas primary care medical providers to assess their knowledge of rabies vaccine procedures and their experience with rabies vaccines. Small town providers within the oral rabies vaccination baiting zone were more aware of rabies prophylaxis (P < 0.03), however, most providers (>95% of 297) rarely saw patients for rabies prophylaxis. Survey data indicated providers have minimal, if any, experience with acquiring and administering rabies prophylaxis. My data suggests that an effective oral rabies vaccination program could be established within urban areas by using short grass area baiting strategies during the fall season, using dip net capturing for faster surveillance collection, and by initiating a rabies education program targeted at Texas’ primary care physicians and their staff.