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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Multi-criteria optimization with dose -volume criteria

Halabi, Tarek 01 January 2007 (has links)
We construct a multi-criteria optimization program that automatically generates the multi-dimensional tradeoff curve of IMRT objectives. Linear convex approximations of non-convex IMRT objectives are used and the Pareto-optimality of approximations in nominal objective space is assessed. Tradeoff solutions are efficiently spread out on the tradeoff curve and an approach for navigating the multi-dimensional curve is shown. The combined effect of column and row generation in speeding up the linear programs is also examined. Our approach is applied to clinical cases and the results examined. An open-source package of our programs, LIRA, is provided.

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