Raphanus raphanistrum L. (wild radish) is a widespread and economically problematic weed of winter crops including wheat (Triticum aestivum L.) in southern Australia. Management of the weed is achieved by a range of non-chemical and chemical techniques. Current management is failing to contain the weed, which is increasing in abundance and distribution. The characteristics of staggered recruitment, dormancy, rapid growth, competitive ability and high levels of seed production contribute to its persistence. The literature review concludes that weeds formed the basis for perpetuation of R. raphanistrum, a claim further investigated by simulation modeling. The effective management of R. raphanistrum should aim to achieve declining populations and this requires the integration of all factors that regulate seed production. Reducing seed production of R. raphanistrum in wheat can be achieved by applying herbicides at reproductive stages of development. This technique has been demonstrated to be an effective, safe and practical method of reducing seed production of R. raphanistrum in wheat. Reducing seed production of R. raphanistrum by herbicides applied at reproductive stages of development is a technique that can be incorporated into an integrated weed management program to improve control / Doctor of Philosophy (PhD)