Graduation date: 1938

No description available.

The ability of human growth hormone (hGH) to alleviate the effects of zinc deficiency on growth was investigated in the rat. Human GH treatment had no significant effect on food consumption, growth parameters or plasma IGF-I. Food consumption, tail length, liver weight, and tibia weight were significantly lower in the zinc deficient group. Body weight was significantly reduced in the zinc deficient and pair fed groups compared to the control. A significant interaction between zinc and hGH was found for tibial epiphyseal cartilage width but there were no significant differences between the groups receiving hGH and the respective shams. Tissue zinc content and plasma alkaline phosphatase were significantly decreased by the dietary zinc deficiency. Plasma zinc was higher in the groups receiving hGH. Significant interactions between zinc and hGH was found for liver iron, tibial zinc, and tibial copper. Copper and iron showed a competitive interaction with zinc and were lower in the rats receiving the control diet. Both lowered zinc and food intake contributed to the effects of the zinc deficiency; however, these effects were not equally distributed. Food intake had the greater effect on growth and plasma IGF-I while tissue mineral content showed a greater effect for zinc intake.

No description available.

published_or_final_version / abstract / Medical Sciences / Master / Master of Medical Sciences

The purpose of this study is to determine the individual and accumulative effect of yellow and white corn meal, cowpeas (black-eyes), fortified oleomargarine, salt pork, molasses, peanuts, cabbage, irradiated evaporated milk, tomatoes, and sweet potatoes upon the nutritional value of the resulting diets.

Bibliography: leaves [11-1]-11-19 / 1 v. (various pagings) : ill ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, 1987

Bibliography: leaves 148-189. / viii, 189 leaves, [5] leaves of plates : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / A transgenic rat model was developed to allow the study of the effects of GH expression, growth regulation and reproductive function. Transgenic rats were created by pronuclear microinjection of a human metallothionein promoter porcine growth hormone (pGH) gene construct. / Thesis (Ph.D.)--University of Adelaide, Dept. of Obstetrics and Gynaecology, 1996?