The purpose of this study was to determine the functional changes due to the Graston Therapeutic Technique (GTT) in an animal model. This study attempted to verify the biomechanical changes associated with the Graston Therapeutic Technique (GTT) in order to possibly apply it to humans as a major physical therapy modality. Eighteen adult, male Sprague-Dawley rats were assigned randomly to three groups. The groups were classified as follows: (a) no injured plus GTT treatment, (b) injured minus GTT treatment, (c) injured plus GTT treatment. The GTT therapy began after one week following injury to allow for optimum inflammation and scar formation. The animals receiving GTT had six treatments over the course of two weeks. Running tests were performed on a treadmill at a velocity of 22 cm/s prior to induction of injury, one week following injury, two weeks following injury, and three weeksfollowing injury in the experimental groups. Variables analyzed were knee and ankle range of motion (ROM), stride length (SL), and stride frequency (SF). Significance of effect between experimental groups were determined by repeated measures one-way ANOVA, Scheffe's post hoc test, and Newman-Keuls post hoc test. The stride length and stride frequency results of the present study appeared to indicate that the Graston Therapeutic Technique (GTT) had an effect on changes in the stride length and stride frequency after injury. Statistical analysis between observations for the GTT plus groups indicated a significant difference in the swing phase of knee ROM. The results of this study also indicated that the Graston Therapeutic Technique may have had an influence on knee joint range of motion. / School of Physical Education