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In the last few years, interest in polymer optical fibers (POF) has increased because of their low cost, easy handling and good flexibility even at large diameters. Moreover, optical cables do not have the problem of electromagnetic interference, which gives, for instance, the problem of cross-talk in copper telephone cables. In the usage of current communication and computer systems the yield has gained a big importance and it has seen from studies that light scattering loss is the only loss, which cannot be eliminated entirely. Besides, this loss causes its attenuation loss intrinsically and determines the lower limit of loss in the POF. In this work, the importance and the dependencies of light scattering were studied, and calculations were done in order to find more appropriate polymer for using as core material of POFs. For this aim, a computer program that calculates the light scattering loss of several amorphous polymers and plots the graph of isotropic scattering loss versus isothermal compressibility and total attenuation loss versus wavelength was written.