Global ETD Search

1	The specificity of platelet glutamate receptor sensitivity as a putative marker for schizophrenia Belsham, Brendan Clive 07 March 2014 (has links) Hypoglutamatergic function is implicated in the pathogenesis of schizophrenia, and supersensitivity of platelet N-methyl-D-aspartate (NMDA) receptors has been reported in schizophrenia. The aim of this study was to examine the platelet glutamate receptor sensitivity in patients with schizophrenia as well as other psychotic conditions, and matched controls, in order to assess if this is a specific marker of schizophrenia or occurs in other psychotic conditions. Glutamate receptor sensitivity was assessed using the intracellular calcium response to glutamate measured with spectrofluorometry. The percentage responses to glutamate stimulation of the schizophrenic subjects and those with depression with psychotic features were significantly greater than control subjects (p<0.005). The mania with psychotic features group was not significantly different to controls. This data suggests that platelet glutamate receptors may be supersensitive in schizophrenia and depression with psychotic features. The platelet may be a possible peripheral marker of glutamate function in schizophrenia and depression with psychotic features. Schizophrenia Receptors, Glutamate
2	[3H](2S,4R)-4-methylglutamate as a novel radioligand for brain glutamate transporters Apricò, Karina, 1977- January 2003 (has links) Abstract not available Neurotransmitters Radioligand assay Glutamates Receptors, Glutamate
3	Identification of post-synaptic receptors mediating eighth nerve function / Irons-Brown, Shunda R. January 2002 (has links) Thesis (Ph. D.)--University of Missouri--Columbia, 2002. / "December 2002." Typescript. Vita. Includes bibliographical references (leaves 117-119). Also issued on the Internet.
4	Modeling disturbances of cholinergic systems : possible relevance for schizophrenia / Mattsson, Anna, January 2005 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 6 uppsatser.
5	Dual effects of kynurenic acid on AMPA receptors / Prescott, Christina Rapp. January 2005 (has links) Thesis (Ph.D. in Neuroscience) -- University of Colorado, 2005. / Typescript. Includes bibliographical references (leaves 116-128). Free to UCDHSC affiliates. Online version available via ProQuest Digital Dissertations;
6	Identification of post-synaptic receptors mediating eighth nerve function Irons-Brown, Shunda R. January 2002 (has links) Thesis (Ph. D.)--University of Missouri--Columbia, 2002. / Typescript. Vita. Includes bibliographical references (leaves 117-119). Also issued on the Internet.
7	Modulation of prefrontal glutamatergic transmission and "atypicality" of antipsychotic drugs / Konradsson, Åsa, January 2007 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
8	Regulation by glutamate- and adenosine-receptors of dopamine and acetylcholine release from rat striatal slices / Jin, Shaoyu. January 1900 (has links) Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 7 uppsatser.
9	Glutamatergic mechanisms in schizophrenia: role of endogenous kynurenic acid / Nilsson, Linda K., January 2005 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 5 uppsatser.
10	Genetic analysis of striatal glutamate-dopamine interactions / Heusner, Carrie L. January 2005 (has links) Thesis (Ph. D.)--University of Washington, 2005. / Vita. Includes bibliographical references (leaves 56-68).

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