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The chemistry of an active adenosine A1 receptor ligand and its related analogs.January 1992 (has links)
by Zhen Yang. / On t.p. "1" is subscript following A in the title. / Thesis (Ph.D.)--Chinese University of Hong Kong, 1992. / Includes bibliographical references (leaves 138-139). / Acknowledgements --- p.i / List of Nomenclature --- p.ii-ix / "Abstracts (for Chapter 2,Chapter 3,and Chapter 4)" --- p.x / Chapter Chapter 1. --- General Introduction --- p.1-8 / Chapter Chapter 2. --- Synthesis of 5-(3-Hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'- hydroxyphenyl)-benzo[b]furan-3-carbaldehyde (XH14) (18) / Chapter 2.1. --- Introduction --- p.9-12 / Chapter 2.2. --- Isolation and Structure Elucidation of XH14 (18) / Chapter 2.2.1. --- Material and method --- p.13-17 / Chapter 2.2.2. --- Structure elucidation --- p.18-23 / Chapter 2.3. --- Results and Discussion / Chapter 2.3.1. --- Total synthesis of XH14 (18) --- p.24-52 / Chapter 2.3.2. --- Chemical modification of XH14 (18) / Chapter (a) --- Synthesis of 3-hydroxymethyl-5-(3-hydroxypropyl)- 7-methoxy-2-(3'-methoxy-4'-hydroxy phenyl)-benzo[b] furan(49) and 3-hydroxymethyl-5-(2-methoxycarbonyl ethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxy phenyl)- benzo[b]furan (66) --- p.53-54 / Chapter (b) --- Synthesis of 5-(2-carboxyethyl)-7-methoxy-2-(3'- methoxy-4'-hydroxyphenyl)-benzo[b]furan-3- carbaldehyde (67) --- p.54 / Chapter (c) --- Synthesis of 5-(3-Hydroxypropyl)-7-methoxy-3- methyl-2-(3'-methoxy-4'-hydroxyphenyl)- benzo[b]furan (68) and 5-(2-methoxycarbonylethyl)-7- methoxy-3-methyl-2-(3'-methoxy-4'-hydroxyphenyl)- benzo[b]furan (69) --- p.54-55 / Chapter (d) --- Synthesis of 5-(2-carboxy-trans-ethenyl)-7- methoxy-2-(3'-methoxy-4'- hydroxy phenyl) benzo[b]furan-3-carbaldehyde (70) --- p.55-56 / Chapter (e) --- Synthesis of 4-bromo-5-(3-hydroxypropyI)-7- methoxy-2-(3'-methoxy-4'- hydroxy phenyl)- benzo[b]furan-3-carbaldehyde (72) --- p.56-57 / Chapter (f) --- Synthesis of 4-acetyl-5-(3-hydroxypropyl)-7- methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-benzo [b]furan (73) and 3-acetyI-5-(3-hydroxypropyl)-7- methoxy-2-(3'-methoxy-4'-hydroxy phenyl)- benzo[b]furan (75) --- p.57-61 / Chapter (g) --- Synthesis of 3-nitro-5-(3-hydroxypropyl)-7- methoxy -2-(3'-methoxy-4'-hydroxyphenyl)- benzo[b]furan (77) and 4-nitro-5-(3-hydroxyphenyl)-7- methoxy-2-(3'-methoxy-4'-hydroxyphenyl)- benzo[b]furan (78) --- p.61-64 / Chapter (h) --- Synthesis of 3-(α-hydroxyethyl)-5-(3-hydroxy propyl) -7-methoxy-2- (3'-methoxy-4' -hydroxyphenyl) - benzo[b]furan (81) --- p.64 / Chapter (i) --- Synthesis of 5-(3-hydroxypropyl)-7-methoxy-2-(3'- methoxy-4'-benzyloxyphenyl )-benzo[b]furan-4- carbaldehyde (82) --- p.64 / Chapter 2.4. --- Structure-activity Relationship of A1 Antagonists --- p.65-71 / Chapter 2.5. --- Conclusion --- p.72 / Chapter 2.6. --- Experimental Section --- p.73-97 / Chapter 2.7. --- References --- p.98-103 / Chapter Chapter 3. --- "Synthesis of 9,10-Dihydro-10,10-dimethoxyanthracen-9-one" / Chapter 3.1. --- Introduction --- p.104 / Chapter 3.2 --- Results and Discussion --- p.105-118 / Chapter 3.3. --- Experimental Section --- p.119-124 / Chapter 3.4. --- References --- p.125-128 / Chapter Chapter 4. --- "Synthesis of 10,11-Dimethoxydibenz[b,f]oxep in" / Chapter 3.1. --- Introduction --- p.129 / Chapter 3.2. --- Results and Discussion --- p.130-133 / Chapter 3.3. --- Experimental Section --- p.134-137 / Chapter 3.4. --- References --- p.138-139 / Appendix / Spectra --- p.140-145
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Structural determinants of P2Y₂ receptor functions /Liu, Jun, January 2003 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2003. / "August 2003." Typescript. Vita. Includes bibliographical references (leaves 82-101). Also issued on the Internet.
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Structural determinants of P2Y₂ receptor functionsLiu, Jun, January 2003 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2003. / "August 2003." Typescript. Vita. Includes bibliographical references (leaves 82-101). Also issued on the Internet.
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Regulation of P2Y₂ nucleotide receptor expression in salivary glands /Ahn, Jae Suk, January 2001 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2001. / "May 2001." Typescript. Vita. Includes bibliographical references (leaves 108-125). Also available on the Internet.
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Adenosine receptor/dopamine receptor interactions : molecular and biochemical aspects /Torvinen, Maria, January 2002 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2002. / Härtill 6 uppsatser.
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Physiology and pathophysiology of central adenosine A1 and A2A receptors /Halldner Henriksson, Linda, January 2003 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 8 uppsatser.
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Adenosine A₂A and ATP receptors in PC12 cells /Arslan, Giulia, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 6 uppsatser.
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Modulation of coronary and skeletal muscle exchange by adenosine : role of adenosine receptors /Wang, Jianjie, January 2005 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2005. / "July 2005." Typescript. Vita. Includes bibliographical references (leaves 196-211). Also issued on the Internet.
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P2 nucleotide receptors during postnatal development of rat salivary glands /Park, Minjung Kang, January 1999 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 1999. / "May 1999." Typescript. Vita. Includes bibliographical references (leaves 108-124). Also available on the Internet.
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Purification and characterization of the human A2A adenosine receptor /Woodard, Robin Leigh. January 1997 (has links)
Thesis (Ph. D.)--University of Virginia, 1997. / Spine title: Human A2A adenosine receptors. Includes bibliographical references (115-135). Also available online through Digital Dissertations.
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