<p dir="ltr">Developing non-invasive and non-destructive testing in complex media continues to be a rich field of study (see e.g.[22, 28, 36, 76, 89] ). These types of tests have applications in medical imaging, geophysical exploration, and engineering where one would like to detect an interior region or estimate a model parameter. With the current rapid development of this enabling technology, there is a growing demand for new mathematical theory and computational algorithms for inverse problems in partial differential equations. Here the physical models are given by a boundary value problem stemming from Electrical Impedance Tomography (EIT), Diffuse Optical Tomography (DOT), as well as acoustic scattering problems. Important mathematical questions arise regarding existence, uniqueness, and continuity with respect to measured surface data. Rather than determining the solution of a given boundary value problem, we are concerned with using surface data in order to develop and implement numerical algorithms to recover unknown subregions within a known domain. A unifying theme of this thesis is to develop Qualitative Methods to solve inverse shape problems using measured surface data. These methods require very few a priori assumptions on the regions of interest, boundary conditions, and model parameter estimation. The counterpart to qualitative methods, iterative methods, typically require a priori information that may not be readily available and can be more computationally expensive. Qualitative Methods usually require more data.</p><p dir="ltr">This thesis expands the library of Qualitative Methods for elliptic problems coming from tomography and scattering theory. We consider inverse shape problems where our goal is to recover extended and small volume regions. For extended regions, we consider applying a modified version of the well-known Factorization Method [73]. Whereas for the small volume regions, we develop a Multiple Signal Classification (MUSIC)-type algorithm (see for e.g. [3, 5]). In all of our problems, we derive an imaging functional that will effectively recover the region of interest. The results of this thesis form part of the theoretical forefront of physical applications. Furthermore, it extends the mathematical theory at the intersection of mathematics, physics and engineering. Lastly, it also advances knowledge and understanding of imaging techniques for non-invasive and non-destructive testing.</p>