This thesis discusses the rise of the Republican party in Texas and specifically Harris County. The time period is the decade between the Presidential election of Dwight D. Eisenhower and the campaign of Jack Cox for Governor. Changes in the structure and leadership of the Republican party at the state level and specific precincts are examined in detail in chapter one. Leaders in Houston during this time period, such as Jesse Jones, Roy Cullen, and Oveta Culp Hobby are discussed in chapter two. The elections of Eisenhower, Cox, and Republican John Tower are analyzed in chapter three. The conclusion finds six major factors for the political changes occurring in Harris County, including economic and demographic changes. Main sources for this work included the Harris County Democratic party records and the Jack Cox Papers at the Center for American History, the Eisenhower Library, and the John Tower Papers.