Thesis (Ph. D.)--Virginia Polytechnic Institute and State University, 1992. / Vita. Abstract. Includes bibliographical references (leaves 147-151). Also available via the Internet.

Thesis (Ph. D.)--Carleton University, 1988. / Also available in electronic format on the Internet.

This work addresses the problem of how an R&D section should decide on a strategy to guide its work when there is no strategic direction supplied from above by the company. The work includes a participant observer case study carried out over five years in a single R&D section, an analysis of research papers on the subject of management of section level R&D, and a review of textbooks on strategy, management and organisational behaviour. From the case study it was concluded that the company itself formed the strategic environment which the strategy of the R&D section had to address, and that the section’s strategic environment was chaotic in the mathematical sense. From the review of management textbooks it was concluded that standard theories do not give usable guidelines for the manager in this situation. A theory was developed that R&D strategy can be thought about in four distinctly different ways. Publications concentrate on two of these, while the case study and surveys of practising managers revealed that the other two were more pertinent in practice. The analysis of research papers was carried out using a newly developed technique, which showed that this body of literature is in a pre-paradigm state. The new technique was also used to show that the four different ways of thinking about R&D are present in the papers. The new literature analysis technique and the theory that R&D strategy can be thought about in four different way were tested by means of questionnaires filled in by authors of papers and by groups of R&D practitioners.

The concept of partnership has in the last decade emerged as being fundamental for successful poverty eradication. The importance of partnerships in development efforts is reflected in high level regional and global commitments and initiatives such as the New Partnership for Africa’s Development (NEPAD) of 2001, the Paris Declaration on Aid Effectiveness of 2005, the Accra Agenda for Action of 2008 and the Busan Partnership for Effective Development Co-operation of 2011. With the emergence of the partnership approach to development, there has also been a significant change in focus and direction of development approaches with new approaches such as Research for Development becoming prominent. Partnerships in Research for Development projects are viewed as important means for contributing to knowledge generation resulting in better and improved services, and development programmes. Although partnerships are believed to be essential in achieving development outcomes, little is known about their impact on the communities which their research is supposed to improve. This thesis examines the impact of research for development partnerships using the Challenge Programme on Water and Food’s (CPWF) Limpopo Basin Development Challenge Programme (LBDC) as a case study. The LBDC was organized into four interlinked technical research projects and one coordination project (L1-L5). The diverse range of partners in the LBDC evident in the range of disciplines and sectors represented in the partnership presented an excellent case study into how different organizations with undoubtedly different mandates come together to work on research for development programmes. The objectives of the study were: to determine the key steps for establishing successful research partnerships; examine how partnerships are communicated to communities and relevant stakeholders paying particular attention to the different communication approaches used and the challenges experienced; assess the success of the partnership in achieving its objectives and the contribution of the partnership to the development of the community; and identify valuable lessons that can be considered by those wanting to replicate, and apply of the partnership approach to other projects. The findings are based on primary and secondary data collected using in-depth semi-structured interviews with 19 LBDC programme partners, qualitative document analysis and participant observation. Results indicate that largely the LBDC partnership was successful in delivering on its objectives as the programme was able to raise awareness of the most up to date available research evidence on agricultural water management and results were shared with basin authorities. Results further support existing knowledge on partnerships and they confirm many of the observations and claims made by established commentators in this field regarding good practice in partnerships. It is clear that the establishment of partnerships is a process that has to be well thought out, the importance of communication within and outside the partnership and external role and stakeholder engagement at all phases of the partnership and especially in monitoring and evaluating the progress of the partnership’s work is crucial. Lessons and recommendations from the study could be valuable to development professionals who carry out their research and development work in partnership. / Dissertation (MSocSc)--University of Pretoria, 2015. / Anthropology and Archaeology / Unrestricted

Includes bibliographical references (leaves 90-93). / Globalization has transformed the world into a big village in which the rich are becoming richer and the poor getting poorer. In the commercial world the trend is for big business to buy out the smaller companies and consequently get bigger. Yet it is arguable that small businesses have assisted in providing much needed services to small communities that occupy informal settlements and exist on or below the poverty datum line. The South African government has amongst its main objectives the alleviation of poverty and the improvement of life in previously disadvantaged communities. The government has allowed the micro-enterprises and small businesses in the informal sector to thrive and in this sector are Spaza shops that supply a wide range of grocery commodities to informal settlements. This paper is about an application framework of soft and hard operational research (OR) techniques used to address the performance of micro-enterprises with Spaza shops in Western Cape as a specific case study. The techniques include Strategic Options Development and Analysis (SODA) using Causal mapping and Soft System Methodology (SSM). These were chosen because of their suitability to understand performance problems faced by Spaza shops owners and find ways of improving the current situation by modelling the intervention of stakeholders. The improvement of Spaza shop businesses is a matter for all stakeholders. Causal mapping, helped to identify and structure the multiple conflicting aspects of Spaza shops business. Soft System Methodology made it possible to conceptualize the intervention model based on the rich picture and root definitions for relevant world-views and see what changes are culturally feasible and systematically desirable. Computer simulations were used to help design and test performance measurement indicators for the Spaza shops so as to enable decision-makers to choose the optimal strategy. Statistical analysis came into account to enable us to capture the seasonality and bring up clustering patterns.

There is a dearth of research on the application of hard Operational Research (OR) techniques (simulation, linear programming, goal programming, etc.) in determining optimal ordering, inventory and allocation policies for goods within distribution systems in developing countries. This study aims to assist decision making at a not-for-profit organization (NPO), Foodbank South Africa (FBSA), within its allocation system through a combined ‘soft-hard’ OR approach. Two problem-structuring tools (soft OR), Causal Mapping (CM) and Soft System Methodology’s Root Definitions (RDs), are used to structure the organization's goals (in order to gain a comprehensive understanding of the decision-context) and gain a better understanding of the ‘decision-issues’ in the allocation system at its Cape Town warehouse.

Includes bibliographical references (leaves 61-64). / Poverty eradication is one of the major challenges facing South Africa and the rest of the continent. Concern around poverty alleviation in South Africa encompasses lack of capacity as well as inefficiency in the management and administration of poverty alleviation projects. Therefore, poverty alleviation agencies ought to be mindful of the issues that could affect their organizational efficiency, especially issues around organizational management. Addressing issues of management amongst the poverty alleviation agencies is necessary to assist role players in the implementation of efficient and effective poverty alleviation programs. The research explored issues around the management structure of a selected non-government organisation (SHAWCO). The objective was to develop a shared understanding of the organizational structure, amongst the members of the management team, and identify (if any) inefficiencies within the structure of the organisation. Problem Structuring Methods have been identified as a collection of tools that assist decision makers in addressing complex societal problems, and seek to alleviate or improve situations characterized by uncertainty, conflict and complexity. The study used Problem Structuring Methods to investigate the possible difficulties SHAWCO is facing as a result of management inefficiency. Interviews were used to uncover issues around the functioning and management of the organization, and an interactive problem structuring workshop was later conducted to develop a shared understanding of the identified issues.

No description available.

Includes abstract. / Includes bibliographical references (p. 89-90). / This thesis proposes the use of data mining tools within an operations research process, allowing the integration of ever increasing amounts of data collected worldwide. It is further argued that the wealth of information delivered by DM tools, with their strong visual emphasis, can be used by enhance the transfer of knowledge of stakeholders. The discipline of operations research could benefit greatly from the methods offered within the field of data mining, used to analyse the ever increasing amounts of data collected worldwide. However, the subject also offers a wealth of information that could aid in decision making, along with visual representations of this information that might assist in the transferral of knowledge to problem stakeholders. The advantages offered by data mining are not limited to problem contexts containing high-quality data, but could also assist within the development contexts containing high-quality data, but could also assist within the development context where traditionally resources and relevant skills are scarce. The benefits of data mining within this context are illustrated through the use of municipal performance data supplied by the Department of Local Government and Housing in the Western Cape of South Africa. The results of these analyses are presented to the department in order to assess the potential contribution of data mining to decisions surrounding municipal support.

Includes bibliographical references (leaves 132-137). / Malaria ranks among the world's most important tropical parasitic diseases with world prevalence figures between 350 and 550 million clinical cases per annum. [WHO, 2008a] 'Treatment and prevention of malaria places a considerable burden on struggling economies where the disease is rampant. Research in malaria does not stop as the change in response to antimalarial drug treatment requires the development of new drugs and innovation in the use of old drugs. This thesis focused on building a model of the spread of resistance to Sulfadoxine/Pyrimethamine (SP) in a setting where both SP and SP in artemisinin-based combination therapy (ACT) are the first line therapies for malaria. The model itself is suitable to any low transmission setting where antimalarial drug resistance exists but the country of choice in this modeling exercise was Mozambique. The model was calibrated using parameters specific to the malaria situation in Mozambique. This model was intended to be used to aid decision making in countries where antimalarial drug resistance exists to help prevent resistance spreading to such an extent that drugs lose their usefulness in curing malaria. The modeling technique of choice was differential equation modeling; a simulation technique that falls under the System Dynamics banner in the Operations Research armamentarium. It is a technique that allowed the modeling of stocks and flows that represent different stages or groupings in the disease process and the rate of movement between these stages respectively. The base model that was built allowed infected individuals to become infectious, to be treated with SP or ACT and to be sensitive to or fail treatment. Individuals were allowed a period of temporary immunity where they would not be reinfected until the residual SP had been eliminated from their bloodstream. The base model was then further developed to include the pharmacokinetic properties of SP where individuals were allowed to be reinfected with certain strains of infection given the level of residual drug in their bloodstream after their current infection had been cleared. The models used in this thesis were built with idea of expanding on previous models and using available data to improve parameter estimates. The model at its core is similar to the resistance model used in Koella and Antia [2003] where differential equation modeling was used to monitor a population as it became infected with a sensitive or resistant infection and then University of Cape Town recovered. The inclusion in the model of the PK component was derived from Prudhomme-O'Meara et al. [2006] where individuals could be reinfected depending on the residual drug in their bloodstream. Rather than modeling simply sensitive and resistant infections, mutations categories were used as was the case in Watkins et al. [2005] population genetics model. The use of mutation categories allowed one to use parameters specific to these categories rather than the sensitive/resistant stratification and this is particularly relevant in Mozambique where all mutation categories still exhibit some degree of sensitivity to treatment i.e. total resistance has not yet developed for any particular mutation category. The last adaptation of the model was to use gametocyte information directly to determine human infectiousness rather than through using a gametocyte switching rate (constant multiplier used to convert parasite density to gametocyte density) as was done in Pongtavompinyo [2006]. The models developed in this thesis found that the existing vector control and drug policy in Mozambique had the major effect of decreasing total prevalence of malaria by approximately 70% in the 11 year period. The distribution of Res3 (presence of DHFR triple) and Res5 (presence of DHFR triple and DHPS double) infections changed over the 11 year period with Res3 infections initially increasing and then decreasing while Res5 infections started low and increased to overtake Res3 infections. The timing of the change in this composition of infection corresponds with the introduction of ACT and thus it appears that the use of ACT prompted the increased prevalence of quintuple parasites over DHFR triple and sensitive parasites. The total number of failures decreased substantially after the introduction of ACT to 17% of its previous level. The results of the base model corresponded with the observed data from the SEACAT study in terms of the magnitude and the trends of the impact of the change to ACT policy, but underestimated the impact of the vector control strategies compared to rapid effect noted in Sharp et al. [2007]. The Scenario testing of the base model showed that vector control is an effective strategy to reduce prevalence and that it is sensitive to the time at which the control is started as it decreased prevalence very gradually. The Scenario testing of the base model also showed that the introduction of ACT in Mozambique had a greater impact on reducing prevalence and that the start time of the ACT strategy did not decrease the effect on prevalence though earlier start times decreased the total number of resistance cases. The ratio of Res5 to Res3 infections increased faster when ACT was the treatment policy than when SP was the policy. Thus higher values of this ratio are associated with ACT being the treatment strategy in place. Thus differential equation modeling is an effective modeling tool to capture the spread of disease and to test the effects of policy interventions as it allows one to assess these effects on populations and averages out individual-level intricacies to better inform policy decisions.