The purpose of the studies presented in this thesis was to develop a greater understanding of the contribution of respiratory heat loss to the thermal balance of exercising horses. In the first experiment the effect of three different warm-up regimens on the thermal balance of Thoroughbred horses was investigated. The experiments showed that a low intensity warm-up was most beneficial aiding heat dissipation during subsequent exercise. The study also showed the heat loss by sweating is not restricted by the rate of sweat production, but by the evaporation rate of the sweat. In the second experiment, horses were exercised to fatigue in thermoneutral and hot-humid environments. The evaporative heat dissipation from sweating and from the respiratory tract was severely impaired during the hot humid exercise protocol. There was a significant increase in the heart rate and the metabolic rate during the hot humid protocol, thus indicating the additional work done by the horse in an effort to dissipate the rapidly accumulating heat. The significantly shorter time to fatigue may be a mechanism to protect the horse from circulatory collapse as the circulatory demands for cardiac output exceed its capacity. In the third experiment adaptations that the horse is able to make to alleviate the compromised evaporative heat loss were identified. These experiments showed that the horse is able to shorten its stride, increase minute ventilation and the velocity of the air in the conducting airways. The results presented also indicate that the horse is able to modify the evaporative area of the airways to enhance evaporative heat loss from the respiratory tract. The experiments also showed that during exercise in hot-humid environments, small changes in the evaporating surface vapour pressure have a significant effect on the vapour pressure gradient thus having a significant effect on the evaporating heat loss. Finally, the lessons gained during the experiments presented in this thesis were used to revise and refine a mathematical model of the thermal balance of exercising horses. The resulting model is more accurate and easier to apply to use in the field. / Thesis (DPhil)--University of Pretoria, 2000. / Equine Research Centre / unrestricted