In the increasingly fierce international competition today, short product life cycle has led to lead time compression and narrow profit margins. Rapid respond to customers has become the key to survival of modern enterprises. Many large corporations in Taiwan have implemented the Toyota¡¦s just-in-time (JIT) production planning approach to reduce inventory to a minimum level, keeping on hand only the amount needed in production until the next order arrives. However, most of those companies have often overlooked that the basic principal of just-in-time replenishment model is the raw materials and other purchased items should be delivered steadily by the supplier when they are needed, and meanwhile those materials from suppliers require no inspection. Nevertheless, it is very difficult to achieve those objectives of JIT Production, especially in an increased market demand. Once some of the suppliers can not meet the delivery time of raw materials and quality is also affected, it would derive lots of problems. This study is aimed to JIT replenishment models on examining firms¡¦ inventory issues. Based on the result of the analysis, it would be the reference to build up the model of quality-oriented embedding collaborative replenishment mechanism for enterprises to improve their JIT replenishment operations. This model, quality-oriented embedding collaborative replenishment model, could assist business in measuring the accurate and precise delivery time and ensuring product quality from suppliers. The research is on the basis of Taiwan optoelectronic industry to investigate the companies of the TFT-LCD panel, and the supply chains of the industry. In analyzing the main TFT-LCD panel providers, the paper will probe into TFT-LCD firms to implement the inventory management system by building the quality-oriented embedding collaborative replenishment mechanism to improve the reaction capacity of businesses, to reduce the risk of raw material quality issues, and to respond to the market rapid change. The study exerts simulation software to conduct simulation and improvement of such models, then according to the simulation results to utilize them as a reference to implementation of quality-oriented embedding collaborative replenishment model into the future operation.