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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
51

TRAIL mediated apoptosis in arthritis.

Dharmapatni, Anak Agung Sagung Sri Kencana January 2007 (has links)
Title page, table of contents and introduction only. The complete thesis in print form is available from the University of Adelaide Library. / Apoptosis and inflammation have been considered to be linked mechanisms. Defective apoptosis may result in cell accumulation and prolonged half life of inflammatory cells in rheumatoid arthritis (RA). A similar phenomenon is seen in malignancy. Therefore, defects in apoptosis pathways that have been proposed to contribute to the pathogenesis of malignancy may also be seen in RA. It has been reported by many studies that treatments that induce apoptosis of malignant cells are advantageous for cancer treatment and this suggests that targeting apoptosis pathways may be important in the management of a variety of pathologies that involve abnormalities in cell proliferation. While apoptosis induction has been a common mechanism in the treatment of cancer, it has only recently been seriously considered to be effective in regulating proliferative cells in inflammation. This thesis provides important information regarding the TRAIL mediated pathway of apoptosis and possible factors that modulate the ability of this pathway to induce apoptosis in RA. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1286764 / Thesis (Ph.D.) -- University of Adelaide, School of Medical Sciences, 2007
52

Applications of real time musculoskeletal ultrasonography in rheumatology practice.

Lee, Anita Tin Yun January 2008 (has links)
Title page, contents and summary only. The complete thesis in print form is available from the University of Adelaide Library. / "In early arthritis, it is important to make a diagnosis before structural damage has occurred, with early disease modifying therapy effective in improving long term outcomes. The first part of this thesis addresses the deficiency in our current knowledge of standardisation and reproducibility of ultrasound (US) findings. Chapter 2 describes a standardised protocol developed for assessing the metacarphphalangeal (MCP) joints and novel measurements of synovial inflammation. Chapter 3 compares early arthritis subjects to a control group, and showed significantly more US synovitis and abnormally increased measurements, with extensor tenosynovitis (ET) and power Doppler (PD_ positivity highly specific to the early arthritis group. Chapter 4 validates HRUS findings in a subset of subjects using MRI as the reference standard..Chapter 5 presents longitudinal data which suggests that clnical swelling and PD positivity at the MCP joints were the most sensitive to change as a reseult of disease-modifying therapy. Chapter 6 validates an US assessment tooldevelopedbadsed on “sentinel joints” whilst factors that may hemp to differentiate subjects with polyarthralgias from those with early RA are identified in chapter 7. The results of this study suggest that early RA needs to be redefined in the light of our US findings. The prognostic value of early US abnormalities will contlinue to be investigated." -- from Abstract. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1317258 / Thesis (Ph.D.) -- University of Adelaide, School of Medicine, 2008
53

TRAIL mediated apoptosis in arthritis.

Dharmapatni, Anak Agung Sagung Sri Kencana January 2007 (has links)
Title page, table of contents and introduction only. The complete thesis in print form is available from the University of Adelaide Library. / Apoptosis and inflammation have been considered to be linked mechanisms. Defective apoptosis may result in cell accumulation and prolonged half life of inflammatory cells in rheumatoid arthritis (RA). A similar phenomenon is seen in malignancy. Therefore, defects in apoptosis pathways that have been proposed to contribute to the pathogenesis of malignancy may also be seen in RA. It has been reported by many studies that treatments that induce apoptosis of malignant cells are advantageous for cancer treatment and this suggests that targeting apoptosis pathways may be important in the management of a variety of pathologies that involve abnormalities in cell proliferation. While apoptosis induction has been a common mechanism in the treatment of cancer, it has only recently been seriously considered to be effective in regulating proliferative cells in inflammation. This thesis provides important information regarding the TRAIL mediated pathway of apoptosis and possible factors that modulate the ability of this pathway to induce apoptosis in RA. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1286764 / Thesis (Ph.D.) -- University of Adelaide, School of Medical Sciences, 2007
54

Rheumatoid arthritis : an overview /

DeLaura, Angela. January 1989 (has links)
Thesis (M.F.A.)--Rochester Institute of Technology, 1989. / Includes bibliographical references (leaves 71-76).
55

Molecular mechanisms of arsenic trioxide in an in vitro model of rheumatoid arthritis synoviocyte

Law, Wai-han, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2009. / Includes bibliographical references (leaves 101-108) Also available in print.
56

An exploratory study of the effectiveness of meditation on patients with rheumatoid arthritis /

Lee, Sui Hong, Philip. January 1996 (has links)
Thesis (M.S.W.)--University of Hong Kong, 1995. / Includes bibliographical references (leaves 106-113).
57

Characteristics of uveitis in juvenile idiopathic arthritis patients in a screening program in Hong Kong

Lau, Wai-ying, Winnie. January 2008 (has links)
Thesis (M.P.H.)--University of Hong Kong, 2008. / Includes bibliographical references (p. 19-20).
58

The diagnostic and prognostic value of anti-CCP assay in the juvenile idiopathic arthritis (JIA)

Hui, Kwun-ho. January 2004 (has links)
Thesis (M. Med. Sc.)--University of Hong Kong, 2004. / Also available in print.
59

Imaging in inflammatory arthritis : a multidisciplinary team approach /

Gibbon, Wayne William. January 2004 (has links) (PDF)
Thesis (M.D.) - University of Queensland, 2005. / Includes bibliography.
60

A comparison between the effects of land and water based exercises in patients with rheumatoid arthritis

Nolte, Kim. January 2005 (has links)
Thesis (M.A.(Biokinetics, Sport and Leisure Sciences))--University of Pretoria, 2002. / Summary in English and Afrikaans. Includes bibliographical references.

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