A large portion of South west Africa/Namibia is underlain by 2 great orogens. They are the Irumide (Sinclair/Rehoboth) and Damara Orogenies. The L-shaped Irumide Province forms part of a belt which extends over the subcontinent from Namaqualand to as far as Zambia. The volcano-sedimentary sequences of the Irumide are believed to have formed in intracratonic rifts and pull-apart basins during the period 1400 to 900 Ma. The evolution of the NW trending Sinclair Group proceeded by means of 3 major cycles each beginning with the emplacement of basic to intermediate magmas followed by felsic ones. The cycle ended off with subsidence, deposition of immature clastic debris and final tilting of the volcano-clastic sequence. It was suggested that the extensive calc-alkaline lavas present, developed within a magmatic arc above a subduction zone, but this proposal has not been generally accepted. The NE trending Klein Aub-Witvlei Basins consist essentially of red bed alluvial fans and lacustrine sediments with minor volcanics near the base. The red beds and aeolian sediments were deposited in an arid climatic condition. The regional greenschist facies metamorphism and deformation is attributed to a major tectono-thermal event at 1100 Ma. The Damara Orogen (900 - 550 Ma) forms part of the Pan-African mobile belt system of global proportions. The NE trending intracontinental branch (aulacogen) and 2 coastal branches constitute a triple junction with its focal point near Swakopmund. The NE extension of the intracontinental belt has been linked with the Lufilian Arc hosting the renown Zambian Copper Belt deposits. In South West Africa/Namibia this belt hosts many different mineral occurrences which can be grouped into rift and collision related deposits. The tectonic history of the Damara Orogen supports a geodynamic-evolution-with-time hypothesis and represents a transitional phase in which limited Wilson Cycle Tectonics was active. The Theory of Mantle Advection is invoked to explain rifting, thinning and subsidence. Extensive ensialic rifting resulted in a relatively stable Northern Carbonate Platform and several deep troughs hosting turbiditic sequences. Crustal rupture in the Khomas Trough allowed for the emplacement of ocean floor tholeiites known as the Matchless Amphibolite Belt. Subsequent ocean closure and collision resulted in deformation, metamorphism and generation of predominantly S-type granites. The southern continental plate was partially overridden by the northern plate during final collision at 550 Ma. These low angle thrust faults allowed for the emplacement of the Naukluft Nappe Complex on top of younger Nama sediments. The break up of Gondwanaland during the Mesozoic with the splitting of the Atlantic Ocean was responsible for the intrusion of anorogenic alkaline ring complexes along the extension of the NE trending transform faults within the intracontinental branch of the Damara Orogen. A close relationship between the tectonic setting and mineral deposits has been recognized in both the Irumide and Damara Orogenies. In the Irumide, stratiform syngenetic copper deposits are hosted by alluvial fan, playa and lacustrine sediments. The uninterrupted sedimentation from the Irumide to Damara Orogen resulted in similar stratiform copper deposits during the early stages of rifting. In the Damara Orogen the rifting (extensional) phase is characterized by 4 main mineralizing systems: diagenetic/syngenetic (Kupferschiefer-type), epigenetic/hydrothermal Cu-Pb-Zn (Mississippi Valley-type), volcanogenic cupriferous pyrite (Besshi-type) and volcano-exhalative Pb-Zn (Red Sea-type). The collision (compressional) phase was accompanied by 4 main mineralizing processes: epigenetic/hydrothermal Cu-Pb-Zn, hydrotheral/metasomatic Sn-W-rare earth, metamorphogenic Au and U-bearing anatectic melts. The key to the selection of viable exploration targets lies in the understanding of the field evidence and the geodynamics modelling to explain the evolution of the orogen and its associated mineral deposits.