Abstract The process of the Israeli-Palestinian negotiation was influenced by the Al Aqsa Intifada. After the "9-11", the American Bush Administration has changed the initial non-involvement policy and proposed the "Roadmap for peace¡¨ with the Quartet to resolve the Israeli-Palestinian conflict. Therefore, this research is based on realism to analyze whether American ¡§Roadmap for peace¡¨ policy does facilitate the peace between Israeli and Palestine or not, and explore how the United States formulates its Israeli-Palestine policy and strategies. Although United States utilizes its superior status and resources to implement the ¡§Roadmap for peace¡¨ , be it the political reform, the security reform, and the economic and humanitarian assistance. The "Roadmap for peace¡¨ is currently worked in the first stage. The reason why is that Israeli and Palestine have different positions on the right of Palestinian refugees back to home, the Jerusalem status, the Jews settlement and border. Besides, both sides inact to fulfill the responsibilities, and still strike each other violently. There are also resistances from within. However, Abbas, who represents the moderate line, has become the new Palestinian President. Israeli Premier Minister Sharon has made compromise in significant issues recently. So long as United States has influence on Israeli and Palestine, and grasps the opportunity to promote ¡§Roadmap for peace¡¨, United States may put into effect the vision, namely peace between Israeli and Palestine.