In this thesis study, a two-fingered gripper and a four-fingered multipurpose gripper are developed and manufactured. In addition to development of robotic hands, computer control hardware and software are also developed for computer control of both hands. The two-fingered gripper is designed for a specially defined pick and place operation. Its task is to pick a cylindrical work piece and place it in the appropriate position in a flexible manufacturing cell. Pneumatic actuator is used for power generation and mechanical links are used for power transmission. Fourfingered gripper is designed as a multipurpose gripper. The task is not predefined for this gripper, so, human hand and previous dexterous hands are taken as model during design. It consists of 3 fingers and a thumb. It has 1 degree of freedom for every finger and thumb. Pneumatic actuators are also used for this gripper. Rope and pulley system is used for the power transmission mechanism. Structures of both hands are manufactured from 5083 series aluminum. Gripping force can be controlled by the pressure regulator of the pneumatic system for both hands. Computer software is developed for the control of open and close motion of the fingers. Also, a motion control card is designed and manufactured for control of the pneumatic valves.

The aim of this thesis is to create the design of a robotic workstation (RWS) for storing bags on a pallets with a capacity of 600 bags per hour. As an introduction to the issues of solved task, the introductory part of the thesis deals with a general information about industrial robots, theories ofdesigning RWS and palletization. For the suggested workstation it is given to have one pickup place from the roller conveyor and two unloading places. Within the RWS it is used belt, roller and chain conveyors as a peripheral device for conveying bags and pallets. There are two variants of RWS created for the possibility of technically - economic assessment. Solution for the security and the ergonomy of the workplace are an integral part of the study. Selected components of RWS have their risk analysis carried out. There is also the draft of a robot gripper mentioned, including assembly drawing. In conclussion there is calculation of returning of funds invested in the construction of RWS. Drawings of robotized workplace disposition, schemes of pneumatic and electrical connections and block diagram of the control system of RWS are included as attachments.

Miniature compliant grippers are designed and developed to manipulate biological cells and characterize them. Apart from grippers, other compliant mechanisms are also demonstrated to be effective in manipulation and characterization. Although scalability and force-sensing capability are inherent to a compliant mechanism, it is important to design a compliant mechanism for a given application. Two techniques based on Spring-lever models and kinetoelastostatic maps are developed and used for designing compliant devices. The kinetoelastostatic maps-based technique is a novel approach in designing a mechanism of a given topology and shape. It is also demonstrated that these techniques can be used to tune the stiffness of a mechanism for a given application. In situations where any single mechanism is incapable of executing a specific task, two or more mechanisms are combined into a single continuum with enhanced functionality. This has led to designs of composite compliant mechanisms. Biological cells are manipulated using compliant grippers in order to study their mechanical responses. Biological cells whose size varies from 1 mm (a large zebrafish embryo) to 10 µm (human liver cells), and which require the grippers to resolve forces ranging from 1 mN (zebrafish embryo) to 10 nN (human cells), are manipulated. In addition to biological cells, in some special cases such as tissue-cutting and cement-testing, inanimate specimens are used to highlight specific features of compliant mechanisms. Two extreme cases of manipulation are carried out to demonstrate the efficacy of the design techniques. They are: (i) breaking a stiff cement specimen of stiffness 250 kN/m (ii) gentle grasping of a soft zebrafish embryo of stiffness 10 N/m. Apart from manipulation, wherever it is viable, the mechanisms are interfaced with a haptic device such that the user’s experience of manipulation is enriched with force feedback. An auxiliary study on the characterization of cells is carried out using a micro¬pipette based aspiration technique. Using this technique, cells existing in different conditions such as perfusion, therapeutic medicines, etc., are mechanically characterized. This study is to qualitatively compare aspiration-based techniques with compliant gripper-based manipulation techniques. A compliant gripper-based manipulation technique is beneficial in estimating the bulk stiffness of the cells and can be extended to estimate the distribution of Young’s modulus in the interior. This estimation is carried out by solving an inverse problem. A previously reported scheme to solve over specified boundary conditions of an elastic object—in this case a cell—is improved, and the improved scheme is validated with the help of macro-scale specimens.