The desire for high performance on scalable parallel systems is increasing the complexity and the need to tune MPI implementations. The MPI Tools Information Interface (MPI T) introduced in the MPI 3.0 standard provides an opportunity for performance tools and external software to introspect and understand MPI runtime behavior at a deeper level to detect scalability issues. The interface also provides a mechanism to fine-tune the performance of the MPI library dynamically at runtime. This thesis describes the motivation, design, and challenges involved in developing an MPI performance engineering infrastructure using MPI T for two performance toolkits — the TAU Performance System, and Caliper. I validate the design of the infrastructure for TAU by developing optimizations for production and synthetic applications. I show that the MPI T runtime introspection mechanism in Caliper enables a meaningful analysis of performance data. This thesis includes previously published co-authored material.