Real-time water quality monitoring using automated systems with sensors is becoming increasingly common, which enables and demands timely identification of unexpected values. Technical issues create anomalies, which at the rate of incoming data can prevent the manual detection of problematic data. This thesis deals with the problem of anomaly detection for water quality data using machine learning and statistic learning approaches. Anomalies in data can cause serious problems in posterior analysis and lead to poor decisions or incorrect conclusions. Five time series anomaly detection techniques: local outlier factor (machine learning), isolation forest (machine learning), robust random cut forest (machine learning), seasonal hybrid extreme studentized deviate (statistic learning approach), and exponential moving average (statistic learning approach) have been analyzed. Extensive experimental analysis of those techniques have been performed on data sets collected from sensors deployed in a wastewater treatment plant. The results are very promising. In the experiments, three approaches successfully detected anomalies in the ammonia data set. With the temperature data set, the local outlier factor successfully detected all twenty-six outliers whereas the seasonal hybrid extreme studentized deviate only detected one anomaly point. The exponential moving average identified ten time ranges with anomalies. Eight of them cover a total of fourteen anomalies. The reproducible experiments demonstrate that local outlier factor is a feasible approach for detecting anomalies in water quality data. Isolation forest and robust random cut forest also rate high anomaly scores for the anomalies. The result of the primary experiment confirms that local outlier factor is much faster than isolation forest, robust random cut forest, seasonal hybrid extreme studentized deviate and exponential moving average. / Thesis / Master of Computer Science (MCS)