The purpose of this study was to compare the relationship between the American College Test (ACT) sub-test scores, nursing courses' grade point average, college cumulative grade point average and the State Board Test Pool Examination (SBTPE) sub-test scores. Data from 227 nurses were analyzed utilizing three procedures: Pearson product-moment coefficient; multiple correlation coefficient; and linear regression equations. Conclusions were that several ACT sub-test scores could yield useful information on admission; the college cumulative grade point average was the most reliable indicator of success on the SBTPE; and an ACT composite score of eleven was the minimum value required to pass the SBTPE sub-tests with a score of at least 350.