International Telemetering Conference Proceedings / October 22-25, 2001 / Riviera Hotel and Convention Center, Las Vegas, Nevada / This article presents a measurement system based on the RS-485 interface. The presented system is an alternative solution for distributed measurement systems, which cannot be built using IEEE-488 interface due to distance limitation between elements of the system. The RS-485 interface is a base for communication between measurement instruments and uses a Master-Slave protocol to exchange data between them. One dedicated master device, usually a PC, controls all slave devices connected to the interface. To control measurement devices SCPI language is used. This solution simplifies communication between measurement devices and allows utilizing the HP-VEE environment to control any SCPI devices connected to the RS-485 network.