Global ETD Search

61	Samčí neplodnost a zlomy DNA v pohlavních buňkách ovlivněných epigenetickým faktorem PRDM9 / Male infertility and DNA germ cell breaks affected by the epigenetic factor PRDM9 Kusari, Fitore January 2021 (has links) DNA-binding histone-3-lysine-4,36-trimethyltransferase PRDM9 specifies meiotic recombination hotspots in mice, rats and humans. Interallelic variation at the Prdm9 locus plays a role in hybrid male sterility. Sterile mouse F1 hybrid male offspring from the PWD × C57BL/6J (B6) cross exhibit meiosis breakdown reminiscent of that observed in Prdm9-deficient B6 sterile mice. However, reciprocal (B6 × PWD)F1 hybrids and some rodent models lacking PRDM9, i.e., PWD and SHR rat males execute meiotic recombination, produce sperm, raising the possibility that PRDM9's role may extend beyond meiosis. Here I demonstrate that PRDM9 is important for post- meiotic male gamete development and release. Unlike their parents, (B6 × PWD)F1 generated spermatozoa of lower quantity and motility but higher percentage of deformations, thus resembling oligoasthenoteratozoospermic (OAT) (semi)sterile men. Histopathological and (ultra)structural analysis revealed compromised spermiogenesis characterized by acrosome detachment and aberrant nucleus elongation in (B6 × PWD)F1 hybrids. Consequently, F1 spermatozoa had malformed acrosomes and nuclear DNA breaks with elevated base oxidation. While deletion of one Prdm9 copy improved sperm phenotypes in (B6 × PWD)F1, copy number gains of the surrounding genes had the opposite effect....
62	Maintenance of the Testis of Acheta Domesticus (L.) In Vitro Dempster, Alastair Robert 03 1900 (has links) No description available. Crickets. Testis. Spermatogenesis.
63	Chromatin variations in bovine spermatogenic cells / Fechheimer, Nathan Stix January 1957 (has links) No description available. Agriculture Chromatin Spermatogenesis in animals
64	Effects of antifertility agents, castration and cryptorchidism on reproductive organs and testosterone levels in adult male rats. Jain, Sughosk Kumar January 1972 (has links) No description available. Biology Spermatogenesis in animals Testosterone
65	Testicular carnitine acetyltransferase activity and serum testosterone levels in developmental stages of the rat and ram / Schanbacher, Bruce Dee January 1973 (has links) No description available. Biology Testis Spermatogenesis in animals
66	The effects of pharmacologically-induced reversible aspermatogenesis and cryptorchidism on serum estrogens of the male rat / Hall, Robert William January 1974 (has links) No description available. Biology Spermatogenesis in animals Testis
67	Ultrastructure of the mature spermatozoa and the process of spermiogenesis in the cockroach, Nauphoeta cinerea (Dictyoptera: Blattaria: Blaberidae) / Kumar, Devi January 1976 (has links) No description available. Biology Cockroaches Spermatogenesis
68	Cell-cell interactions in the rat testis: biology and future perspectives 鍾穗華, Chung, Shui-wah. January 1999 (has links) published_or_final_version / Zoology / Doctoral / Doctor of Philosophy Germ cells Spermatogenesis. Rats - Physiology.
69	Biology of junction dynamics in the testis and its implications in male contraceptive development Lee, Pui-yue, Nikki., 李珮瑜. January 2003 (has links) published_or_final_version / Zoology / Doctoral / Doctor of Philosophy Spermatogenesis. Cell junctions. Male contraception.
70	Molecular and functional characterization of a testis-specific TRS4 gene in spermatogenesis Tang, Yue-bun, Alan., 鄧裕斌. January 2010 (has links) published_or_final_version / Obstetrics and Gynaecology / Master / Master of Philosophy Mice.

Search results