Because computer use become more and more important in the educational environment, the attitudes of students toward computer may play an important role in their learning success. This study investigated the attitudes toward computers and gender differences of sixth-grade Kuwaiti students and examined the relationships between students’ attitudes toward computers and school, motivation/persistence, study habits, empathy, creative tendencies, and achievement in the Informatics field. The Computer Attitude Questionnaire (CAQ), translated from the English into Arabic Language for this study, was originally developed by Knezek and Miyashita for the Texas Center for Educational Technology (University of North Texas). The CAQ was administered to a random cluster sample of 10 public middle schools: (5 boys’ and 5 girls’ schools), with a total of 562 students, (265 boys and 297 girls), in the State of Kuwait during the academic year 1999-2000. The pilot test was conducted to calculate the reliability with Cronbach’s alpha = .87 for the CAQ Arabic version. This study found positive attitudes toward computer use (mean = 3.31 on 4-point Likert-scale); however, girls had significantly more positive attitudes toward computers (mean = 3.36) than did boys (mean = 3.26). It also found statistically significant correlations between attitudes toward computers and school (r. = .149), motivation/persistence (r. = .459), study habits (r. = .371), empathy (r. = .308), creative tendencies (r. = .530), and achievement in the Informatics field (r. = .201). A statistically significant gender difference was found in the correlations between attitudes toward computers and empathy. Girls had a stronger correlation (r. = .405) than boys (r. = .215). This study also found that students who use computers at home (mean = 3.40) have more positive attitudes toward computers than did students who do not (mean = 3.22). The main conclusion of the current study is that students like to use computers, therefore, the researcher suggests that computer should be introduced for the students in the classrooms environment and to be integrated into the curriculum of all subject areas.