This is an exploratory study that seeks to establish the extent to which traditional theologies on 'imago Dei' may contribute to the vulnerability of Catholic single women to HIV and AIDS. It employs a feminist framework of study to critically analyse how androcentric theologies on imago Dei informed by the Greek philosophies of Plato and Aristotle and advanced by the Church fathers do contribute to the dehumanisation of women. Argued in this study, is that these teachings could be responsible for single women‟s vulnerability in the context of HIV and AIDS. Following extensive research done on women, HIV and AIDS, this study also presents cultural, social, economic and religious factors as players in women‟s susceptibility to HIV and AIDS. However, in a unique and particular way, this study seeks and presents a possible connection between the Catholic Church‟s teachings on imago Dei and the vulnerability of Catholic single women to HIV and AIDS. / Thesis (M.A.)-University of KwaZulu-Natal, Pietermaritzburg, 2011.