In developing countries, 60% of project management professionals appear to lack knowledge that timely completion, budget fidelity, and high quality are critical success factors for completion of construction initiatives. Based on the theories of iron triangle, accident causation, scientific management, and strategic management, the purpose of this correlational study was to examine the relationship between project budget and the independent variables of time, quality, safety, environmental impact, and site disputes in the Greater Accra Region of Ghana. One hundred and sixteen project managers, randomly selected from the population of construction professionals in the Greater Accra Region of Ghana, completed the survey entitled the Six Key Performance Indicators developed by Ngacho and Das (2014). The results of the multiple linear regression analysis indicated a weak positive correlation exists between the independent variables (time, quality, safety, environmental impact, and site disputes) and project budget, F(1, 114) = 37.08, p < 0.001. Time recorded the highest beta (β = .50) followed by site dispute (β = .29), environment (β = .22), quality (β = .06), and safety (β = .04). Attention to key performance indicators associated with time, dispute, and environmental impact could improve project outcomes in the Ghanaian construction sector. The study findings could be useful to improve the quality of projects and may benefit the lives of professionals and community members in the area.