Thesis (Ph. D.)--School of Dentistry and School of Pharmacy. University of Missouri--Kansas City, 2007. / "A dissertation in oral biology and pharmacology" Advisor: Carole McArthur. Typescript. Vita. Title from "catalog record" of the print edition Description based on contents viewed Sept. 15, 2008. Includes bibliographical references (leaves 137-151). Online version of the print edition.

Thesis (Ph. D.)--School of Biological Sciences. University of Missouri--Kansas City, 1999. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 138-153). Includes bibliographical references.

Thesis (Ph. D.)--School of Biological Sciences. University of Missouri--Kansas City, 1999. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 138-153). Includes bibliographical references.

No description available.

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Thesis (M.S.)--University of Florida, 2004. / Typescript. Title from title page of source document. Document formatted into pages; contains 62 pages. Includes Vita. Includes bibliographical references.

Thesis (Ph. D.)--University of Hong Kong, 2007. / Title proper from title frame. Also available in printed format.

Thesis (Ph. D.)--University of Virginia, 2006. / Includes bibliographical references. Also available online through Digital Dissertations.

Sjogren’s syndrome (SS) is a systemic autoimmune disease that presents to eye care practitioners with the hallmark symptom of “dry eye.” Stratifying dry eye patients as Sjogren’s positive or negative is a critical differential diagnosis, as SS patients have numerous systemic complications and a forty times greater risk of developing lymphoma. As such, management of this relatively common dry eye sub-population requires specialized care. Since a firm diagnosis requires testing that is both invasive and expensive, patients should be protected from these tests if they are not warranted. In this thesis, studies were therefore undertaken to determine if SS dry eye could be differentiated from other forms of dry eye using two methods: 1) standard clinical tests used in a multi-disciplinary Sjogren’s syndrome clinic and 2) subsequent biological evaluation of collected tear samples and cells from the ocular surface. The former would allow eye care practitioners to conduct appropriate tests and pose suitable questions to ifferentiate these subgroups, and the latter might serve in the future as a relatively non-invasive quantitative means of differentiating such groups through biomarkers.

Sjogren’s syndrome (SS) is a systemic autoimmune disease that presents to eye care practitioners with the hallmark symptom of “dry eye.” Stratifying dry eye patients as Sjogren’s positive or negative is a critical differential diagnosis, as SS patients have numerous systemic complications and a forty times greater risk of developing lymphoma. As such, management of this relatively common dry eye sub-population requires specialized care. Since a firm diagnosis requires testing that is both invasive and expensive, patients should be protected from these tests if they are not warranted. In this thesis, studies were therefore undertaken to determine if SS dry eye could be differentiated from other forms of dry eye using two methods: 1) standard clinical tests used in a multi-disciplinary Sjogren’s syndrome clinic and 2) subsequent biological evaluation of collected tear samples and cells from the ocular surface. The former would allow eye care practitioners to conduct appropriate tests and pose suitable questions to ifferentiate these subgroups, and the latter might serve in the future as a relatively non-invasive quantitative means of differentiating such groups through biomarkers.